catalog number :
MBS2025723
products full name :
Monoclonal Antibody to Interleukin 6 (IL6)
products short name :
[Interleukin 6]
other names :
[interleukin-6; Interleukin-6; interleukin-6; interleukin 6]
products gene name :
[IL6]
other gene names :
[Il6; Il6; ILg6; Ifnb2; Il-6; IL-6]
purity :
Protein A + Protein G affinity chromatography
form :
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3, 50% glycerol
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
tested application :
WB; IHC; ICC; IP.
app notes :
Western blotting: 0.5-2 ug/mL;1:500-2000 . Immunohistochemistry: 5-20 ug/mL;1:50-200. Immunocytochemistry: 5-20 ug/mL;1:50-200. Optimal working dilutions must be determined by end user.
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
image3 heading :
Immunohistochemistry (IHC)
image4 heading :
Immunohistochemistry (IHC)
image4 description :
DAB staining on IHC-P Samples:Rat Heart Tissue)
image5 heading :
Immunohistochemistry (IHC)
image5 description :
DAB staining on IHC-P Samples:Rat Skeletal Muscle Tissue
other info1 :
Organism Species: Rattus norvegicus (Rat)
other info2 :
Conjugate: No Conjugate. Immunogen: Recombinant IL6 (Thr21~Thr211) expressed in E Coli. Conjugated Antibody: The APC conjugated antibody version of this item is also available as catalog #MBS2037119
ncbi acc num :
NP_036721.1
ncbi gb acc num :
NM_012589.2
ncbi pathways :
Adipogenesis Pathway (198479); African Trypanosomiasis Pathway (194377); African Trypanosomiasis Pathway (194323); Amoebiasis Pathway (167311); Amoebiasis Pathway (167191); Androgen Receptor Signaling Pathway (198529); Chagas Disease (American Trypanosomiasis) Pathway (147806); Chagas Disease (American Trypanosomiasis) Pathway (147795); Cytokine Signaling In Immune System Pathway (829152); Cytokine-cytokine Receptor Interaction Pathway (83443)
ncbi summary :
a cytokine involved in development and possibly in neurodegenerative processes [RGD, Feb 2006]
uniprot summary :
Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation ().