catalog number :
MBS2025650
products full name :
Monoclonal Antibody to Arginase (ARG)
products short name :
[Arginase]
other names :
[arginase-1; Arginase-1; arginase-1; arginase 1; Liver-type arginase; Type I arginase]
products gene name :
[ARG]
other gene names :
[Arg1; Arg1]
specificity :
The antibody is a Mouse monoclonal antibody raised against ARG. It has been selected for its ability to recognize ARG in immunohistochemical staining and western blotting.
purity :
Protein A/G Affinity Chromatography
form :
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
tested application :
WB; IHC; ICC; IP
app notes :
Western blotting: 0.5-5µg/mL. Immunohistochemistry: 5-30µg/mL. Immunocytochemistry: 5-30µg/mL. Optimal working dilutions must be determined by end user
image1 heading :
Western Blot (WB)
image2 heading :
Western Blot (WB)
image3 heading :
Immunohistochemistry (IHC)
image4 heading :
Immunohistochemistry (IHC)
image4 description :
DAB staining on IHC-P Samples:Rat Kidney Tissue)
image5 heading :
Immunohistochemistry (IHC)
image5 description :
DAB staining on IHC-P Samples:Rat Stomach Tissue)
other info1 :
Source: Monoclonal antibody preparation. Traits: Liquid. Immunogen: Recombinant ARG (Met1~Lys323) expressed in E.coli.
other info2 :
Conjugated Antibody: The APC conjugated antibody version of this item is also available as catalog #MBS2051741
ncbi acc num :
NP_058830.2
ncbi gb acc num :
NM_017134.3
ncbi mol weight :
34,973 Da
ncbi pathways :
Amoebiasis Pathway (167311); Amoebiasis Pathway (167191); Arginine And Proline Metabolism Pathway (83349); Arginine And Proline Metabolism Pathway (323); Arginine Biosynthesis Pathway (83336); Arginine Biosynthesis Pathway (306); Biosynthesis Of Amino Acids Pathway (791250); Biosynthesis Of Amino Acids Pathway (795174); Metabolic Pathways (132933); Metabolism Pathway (1333271)
ncbi summary :
catalyzes the hydrolysis of arginine to ornithine and urea in arginine metabolism; regulates nitric oxide production [RGD, Feb 2006]
uniprot summary :
ARG1: Homotrimer. By arginine or homoarginine. Belongs to the arginase family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Amino Acid Metabolism - arginine and proline; EC 3.5.3.1; Hydrolase. Chromosomal Location of Human Ortholog: 1p12. Cellular Component: cell soma; cytoplasm; extracellular space; mitochondrial outer membrane; neuron projection; nucleus. Molecular Function: arginase activity; manganese ion binding. Biological Process: aging; arginine catabolic process to ornithine; arginine metabolic process; collagen biosynthetic process; defense response to protozoan; female pregnancy; liver development; lung development; mammary gland involution; maternal process involved in female pregnancy; negative regulation of activated T cell proliferation; negative regulation of T cell proliferation; positive regulation of endothelial cell proliferation; response to amine; response to amino acid; response to axon injury; response to cadmium ion; response to drug; response to herbicide; response to lipopolysaccharide; response to manganese ion; response to methylmercury; response to peptide hormone; response to selenium ion; response to steroid hormone; response to vitamin A; response to vitamin E; response to wounding; response to zinc ion; urea cycle