Mucin 5 Subtype B (MUC5B) ELISA Kit | MyBioSource MBS2024599 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Mucin 5 Subtype B (MUC5B) ELISA Kit

catalog :

MBS2024599

quantity :

24-Strip-Wells

price :

255 USD

more info or order :

MyBioSource product webpage

image

image 1 :

product information

catalog number :

MBS2024599

products type :

ELISA Kit

products full name :

Mucin 5 Subtype B (MUC5B) ELISA Kit

products short name :

[Mucin 5 Subtype B (MUC5B)]

products name syn :

[MUC5-B; MUC9; MG1; Oligomeric Mucus/Gel-Forming; Mucin 5,Subtype B,Tracheobronchial; Cervical mucin; High molecular weight salivary mucin MG1; Sublingual gland mucin]

other names :

[mucin-5B; Mucin-5B; mucin-5B; mucin 5B, oligomeric mucus/gel-forming; Cervical mucin; High molecular weight salivary mucin MG1; Mucin-5 subtype B, tracheobronchial; Sublingual gland mucin]

products gene name :

[MUC5B]

other gene names :

[MUC5B; MUC5B; MG1; MUC5; MUC9; MUC-5B; MUC5; MUC-5B]

uniprot entry name :

MUC5B_HUMAN

reactivity :

Human

sequence length :

5762

specificity :

This assay has high sensitivity and excellent specificity for detection of MUC5B. No significant cross-reactivity or interference between MUC5B and analogues was observed.

storage stability :

The stability of kit is determined by the loss rate of activity. The loss rate of this kit is less than 5% within the expiration date under appropriate storage condition. To minimize extra influence on the performance, operation procedures and lab conditions, especially room temperature, air humidity, incubator temperature should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same operator from the beginning to the end.

image1 heading :

Typical Testing Data/Standard Curve (for reference only)

other info1 :

Samples: human tissue homogenates, cell lysates, cell culture supernates and other biological fluids. Detection Range: 0.312-20ng/mL. Sensitivity: <0.115ng/mL

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): 3 samples with low, middle and high level MUC5B were tested 20 times on one plate, respectively. Intra-Assay: CV<10%. Inter-assay Precision: Inter-assay Precision (Precision between assays): 3 samples with low, middle and high level MUC5B were tested on 3 different plates, 8 replicates in each plate. CV(%) = SD/meanX100. Inter-Assay: CV<12%

products categories :

Tumor immunity; Infection immunity; Pulmonology; Dermatology

products description :

Intended Uses: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of MUC5B in human tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

ncbi gi num :

301172750

ncbi acc num :

NP_002449.2

ncbi gb acc num :

NM_002458.2

ncbi mol weight :

596,340 Da

ncbi pathways :

Metabolism Of Proteins Pathway (106230); O-linked Glycosylation Pathway (1127679); O-linked Glycosylation Of Mucins Pathway (530747); Post-translational Protein Modification Pathway (161012); Salivary Secretion Pathway (153376); Salivary Secretion Pathway (153352); Termination Of O-glycan Biosynthesis Pathway (530748)

ncbi summary :

This gene encodes a member of the mucin family of proteins, which are highly glycosylated macromolecular components of mucus secretions. This family member is the major gel-forming mucin in mucus. It is a major contributor to the lubricating and viscoelastic properties of whole saliva, normal lung mucus and cervical mucus. This gene has been found to be up-regulated in some human diseases, including sinus mucosa of chronic rhinosinusitis (CRS), CRS with nasal polyposis, chronic obstructive pulmonary disease (COPD) and H. pylori-associated gastric disease, and it may be involved in the pathogenesis of these diseases. [provided by RefSeq, Jul 2010]

uniprot summary :

MUC5B: Gel-forming mucin that is thought to contribute to the lubricating and viscoelastic properties of whole saliva and cervical mucus. Defects in MUC5B are a cause of susceptibility to pulmonary fibrosis idiopathic (IPF). Pulmonary fibrosis is a lung disease characterized by shortness of breath, radiographically evident diffuse pulmonary infiltrates, and varying degrees of inflammation and fibrosis on biopsy. It results in acute lung injury with subsequent scarring and endstage lung disease. A common polymorphism in the promoter of MUC5B is associated with familial interstitial pneumonia and idiopathic pulmonary fibrosis, suggesting that dysregulated MUC5B expression in the lung may be involved in the pathogenesis of pulmonary fibrosis (PubMed:21506741). Protein type: Cell adhesion; Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 11p15.5. Cellular Component: extracellular space; Golgi lumen. Molecular Function: protein binding. Biological Process: protein amino acid O-linked glycosylation; cellular protein metabolic process; O-glycan processing; regulation of macrophage activation; defense response to bacterium; post-translational protein modification. Disease: Pulmonary Fibrosis, Idiopathic

size1 :

24-Strip-Wells

price1 :

255 USD

size2 :

48-Strip-Wells

price2 :

455

size3 :

96-Strip-Wells

price3 :

610

size4 :

5x96-Strip-Wells

price4 :

2470

size5 :

10x96-Strip-Wells

price5 :

4445

more info or order :

MyBioSource product webpage