catalog number :
MBS2020775
products type :
ELISA Kit
products full name :
Chemokine C-X-C-Motif Ligand 16 (CXCL16) ELISA Kit
products short name :
[Chemokine C-X-C-Motif Ligand 16 (CXCL16)]
products name syn :
[SR-PSOX; CXCLG16; SRPSOX; Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein; Small-inducible cytokine B16]
other names :
[chemokine (C-X-C motif) ligand 16; C-X-C motif chemokine 16; C-X-C motif chemokine 16; chemokine (C-X-C motif) ligand 16; Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein; SR-PSOX; Small-inducible cytokine B16; Transmembrane chemokine CXCL16]
products gene name :
[CXCL16]
other gene names :
[CXCL16; CXCL16; SRPSOX; CXCLG16; SR-PSOX; SCYB16; SRPSOX; SR-PSOX]
uniprot entry name :
CXL16_HUMAN
specificity :
This assay has high sensitivity and excellent specificity for detection of CUX2. No significant cross-reactivity or interference between CUX2 and analogues was observed.
storage stability :
The stability of kit is determined by the loss rate of activity. The loss rate of this kit is less than 5% within the expiration date under appropriate storage condition. To minimize extra influence on the performance, operation procedures and lab conditions, especially room temperature, air humidity, incubator temperature should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same operator from the beginning to the end.
image1 heading :
Typical Testing Data/Standard Curve (for reference only)
other info1 :
Samples: Human Tissue Homogenates, Cell Lysates And Other Biological Fluids. Assay Type: Quantitative Sandwich. Detection Range: 0.312-20ng/mL. Sensitivity: 0.113ng/mL.
other info2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): 3 samples with low, middle and high level CUX2 were tested 20 times on one plate, respectively. Intra-Assay: CV<10%. Inter-assay Precision: Inter-assay Precision (Precision between assays): 3 samples with low, middle and high level CUX2 were tested on 3 different plates, 8 replicates in each plate. CV(%) = SD/meanX100. Inter-Assay: CV<12%
products categories :
Cytokine; Tumor immunity; Infection immunity
products description :
Intended Uses: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of CUX2 in human tissue homogenates, cell lysates and other biological fluids. Principle of the Assay: The microplate provided in this kit has been pre-coated with an antibody specific to CUX2. Standards or samples are then added to the appropriate microplate wells with a biotin-conjugated antibody specific to CUX2. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain CUX2, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm +/- 10nm. The concentration of CUX2 in the samples is then determined by comparing the O.D. of the samples to the standard curve.
ncbi acc num :
EAW90416.1
ncbi mol weight :
27,579 Da
ncbi pathways :
Chemokine Receptors Bind Chemokines Pathway (106359); Chemokine Signaling Pathway (99051); Chemokine Signaling Pathway (96864); Class A/1 (Rhodopsin-like Receptors) Pathway (106357); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway (1127664); Disease Pathway (530764); G Alpha (i) Signalling Events Pathway (119550); GPCR Downstream Signaling Pathway (119548)
uniprot summary :
CXCL16: Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis. Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo. Belongs to the intercrine alpha (chemokine CxC) family. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 17p13. Cellular Component: extracellular space; membrane; extracellular region; integral to membrane; plasma membrane. Molecular Function: low-density lipoprotein receptor activity; chemokine activity; scavenger receptor activity. Biological Process: receptor-mediated endocytosis; response to cytokine stimulus; chemotaxis; positive regulation of cell growth; positive regulation of cell migration
size5 :
10x96-Strip-Wells