A Disintegrin And Metalloproteinase With Thrombospondin 5 (ADAMTS5) ELISA Kit | MyBioSource MBS2020569 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

A Disintegrin And Metalloproteinase With Thrombospondin 5 (ADAMTS5) ELISA Kit

catalog :

MBS2020569

quantity :

24-Strip-Wells

price :

270 USD

more info or order :

MyBioSource product webpage

image

image 1 :

product information

catalog number :

MBS2020569

products type :

ELISA Kit

products full name :

A Disintegrin And Metalloproteinase With Thrombospondin 5 (ADAMTS5) ELISA Kit

products short name :

[A Disintegrin And Metalloproteinase With Thrombospondin 5 (ADAMTS5)]

products name syn :

[ADMP-2; Aggrecanase-2]

other names :

[A disintegrin and metalloproteinase with thrombospondin motifs 5 preproprotein; A disintegrin and metalloproteinase with thrombospondin motifs 5; A disintegrin and metalloproteinase with thrombospondin motifs 5; ADAM metallopeptidase with thrombospondin type 1 motif, 5; A disintegrin and metalloproteinase with thrombospondin motifs 11; ADAM-TS 11; ADAMTS-11; ADMP-2; Aggrecanase-2]

products gene name :

[ADAMTS5]

other gene names :

[ADAMTS5; ADAMTS5; ADMP-2; ADAM-TS5; ADAMTS-5; ADAMTS11; ADAM-TS 5; ADAMTS-11; ADAM-TS 11; ADAMTS11; ADMP2; ADAM-TS 5; ADAM-TS5; ADAMTS-5; ADAM-TS 11; ADAMTS-11]

uniprot entry name :

ATS5_HUMAN

reactivity :

Human

sequence length :

930

specificity :

This assay has high sensitivity and excellent specificity for detection of ADAMTS5. No significant cross-reactivity or interference between ADAMTS5 and analogues was observed.

storage stability :

The stability of kit is determined by the loss rate of activity. The loss rate of this kit is less than 5% within the expiration date under appropriate storage condition. To minimize extra influence on the performance, operation procedures and lab conditions, especially room temperature, air humidity, incubator temperature should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same operator from the beginning to the end.

image1 heading :

Typical Testing Data/Standard Curve (for reference only)

other info1 :

Samples: human serum, plasma, tissue homogenates and other biological fluids. Detection Range: 0.312-20ng/mL. Sensitivity: <0.127ng/mL

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): 3 samples with low, middle and high level ADAMTS5 were tested 20 times on one plate, respectively. Intra-Assay: CV<10%. Inter-assay Precision: Inter-assay Precision (Precision between assays): 3 samples with low, middle and high level ADAMTS5 were tested on 3 different plates, 8 replicates in each plate. CV(%) = SD/meanX100. Inter-Assay: CV<12%

products categories :

Enzyme & Kinase

products description :

Intended Uses: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of ADAMTS5 in human serum, plasma, tissue homogenates and other biological fluids.

ncbi gi num :

195539372

ncbi acc num :

NP_008969.2

ncbi gb acc num :

NM_007038.3

uniprot acc num :

Q9UNA0

ncbi mol weight :

101,718 Da

ncbi pathways :

Degradation Of The Extracellular Matrix Pathway (576263); Endochondral Ossification Pathway (198812); Extracellular Matrix Organization Pathway (576262); Metabolism Of Proteins Pathway (106230); O-glycosylation Of TSR Domain-containing Proteins Pathway (1127680); O-linked Glycosylation Pathway (1127679); Post-translational Protein Modification Pathway (161012)

ncbi summary :

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs and functions as aggrecanase to cleave aggrecan, a major proteoglycan of cartilage. [provided by RefSeq, Jul 2008]

uniprot summary :

ADAMTS5: Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. May play a role in proteolytic processing mostly during the peri-implantation period. Protein type: EC 3.4.24.-; Extracellular matrix; Motility/polarity/chemotaxis; Secreted; Protease; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 21q21.3. Cellular Component: proteinaceous extracellular matrix; endoplasmic reticulum lumen; extracellular region. Molecular Function: integrin binding; protein binding; metallopeptidase activity; zinc ion binding; metalloendopeptidase activity. Biological Process: extracellular matrix disassembly; protein amino acid O-linked glycosylation; extracellular matrix organization and biogenesis; cellular protein metabolic process; defense response to bacterium; post-translational protein modification; proteolysis

size1 :

24-Strip-Wells

price1 :

270 USD

size2 :

48-Strip-Wells

price2 :

495

size3 :

96-Strip-Wells

price3 :

665

size4 :

5x96-Strip-Wells

price4 :

2715

size5 :

10x96-Strip-Wells

price5 :

4895

more info or order :

MyBioSource product webpage