catalog number :
MBS202002
products full name :
Gamma-Synuclein antibody
products short name :
Gamma-Synuclein
products name syn :
SNCG; BCSG1; PERSYN; PRSN; gamma-Synuclein; Persyn; Breast cancer-specific gene 1 protein; Synoretin; SR; gamma-synuclein; gamma synuclein; Synuclein; gamma (breast cancer-specific protein 1) BCSG 1; Breast cancer specific gene 1; Breast cancer specific gene 1 protein; Breast cancer specific protein 1; Gamma synuclein; SNCG protein; SR; Synuclein gamma
other names :
gamma-synuclein; Gamma-synuclein; gamma-synuclein; breast cancer-specific gene 1 protein; persyn; synoretin; synuclein, gamma (breast cancer-specific protein 1); Breast cancer-specific gene 1 protein; Persyn; Synoretin; SR
other gene names :
SNCG; SNCG; SR; BCSG1; BCSG1; PERSYN; PRSN; SR
uniprot entry name :
SYUG_HUMAN
purity :
By protein-A affinity chromatography
form :
Liquid. Supplied in Phosphate-Buffered Saline (pH 7.4) with 0.1% Sodium Azide.
storage stability :
Can be stored at 4 degree C. For long term storage, aliquot and store at -20 degree C. Avoid repeated freezing and thawing cycles.
tested application :
ELISA (EIA), Western Blot (WB)
app notes :
The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:500 ~ 2,000. Recommended starting dilution is 1:1,000.
other info1 :
Antigen Species: Human. Immunogen: Recombinant human gamma-Synuclein (1-127aa)
products categories :
Neuroscience
products description :
Synucleins are small, soluble proteins expressed primarily in neural tissue and in certain tumors. The family includes three known proteins: alpha-synuclein, beta-synuclein, and gamma-synuclein. All synucleins have in common a highly conserved alpha-helical lipid-binding motif with similarity to the class-A2 lipid-binding domains of the exchangeable apolipoproteins. Although they are homologous, each synuclein is encoded by a different gene on chromosomes 4q21.3-q22. gamma-Synuclein (also called BCSG-1) is abnormally expressed in a high percentage of tumor tissues of diversified cancer types, including liver, esophagus, colon, gastric, lung, prostate, cervical, and breast cancer.
products references :
Liu H. et. al. (2005) Cancer Res. 65, 7635-7643 Ji.H. et al. (1997)) Cancer Res. 57, 759-764 George, J.M. (2001) Genome Biol. 3, 3002.1-3002.6
ncbi acc num :
NP_003078.2
ncbi gb acc num :
NM_003087.2
ncbi mol weight :
13,331 Da
ncbi summary :
This gene encodes a member of the synuclein family of proteins which are believed to be involved in the pathogenesis of neurodegenerative diseases. Mutations in this gene have also been associated with breast tumor development. [provided by RefSeq, Jan 2010]