catalog number :
MBS2018594
products type :
Recombinant Protein
products full name :
Recombinant Gastrin (GT)
products short name :
[Gastrin (GT)]
other names :
[gastrin preproprotein; Gastrin; gastrin; preprogastrin; gastrin; Gastrin component IGastrin-52; G52Big gastrin; Alternative name(s):; Gastrin component II; Gastrin-34; G34Gastrin; Alternative name(s):; Gastrin component III; Gastrin-17]
products gene name :
[GT]
other gene names :
[GAST; GAST; GAS; GAS; G52; G34; G17; G14; G6]
uniprot entry name :
GAST_HUMAN
form :
20mM Tris, 150mM NaCl, pH8.0, containing 0.01% SKL, 5% Trehalose.
concentration :
Original Concentration: 100ug/mL
storage stability :
Storage:. Avoid repeated freeze/thaw cycles. Store at 2-8ºC for one month. Aliquot and store at -80ºC for 12 months. Stability Test:. The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
tested application :
Positive Control; Immunogen; SDS-PAGE; Western Blot (WB).
image1 heading :
Sequence
image2 heading :
Identification
image3 heading :
SDS-Page
other info1 :
Organism Species: Homo sapiens (Human). Source: Prokaryotic expression. Residues: Met1~Asn101. Tags: N-terminal His and GST Tag. Subcellular Location: Secreted
other info2 :
Traits: Freeze-dried powder. Predicted isoelectric point: 5.8. Usage: Reconstitute in ddH2O to a concentration of 0.1-1.0 mg/mL. Do not vortex.
ncbi acc num :
NP_000796.1
ncbi gb acc num :
NM_000805.4
ncbi mol weight :
Predicted Molecular Mass: 41.4kDa. Accurate Molecular Mass: 42kDa as determined by SDS-PAGE reducing conditions.
ncbi pathways :
G Alpha (q) Signalling Events Pathway (106043); GPCR Downstream Signaling Pathway (119548); Gastric Acid Secretion Pathway (154409); Gastric Acid Secretion Pathway (154383); Gastrin-CREB Signalling Pathway Via PKC And MAPK (645295); Signal Transduction Pathway (477114); Signaling By GPCR Pathway (106356)
ncbi summary :
Gastrin is a hormone whose main function is to stimulate secretion of hydrochloric acid by the gastric mucosa, which results in gastrin formation inhibition. This hormone also acts as a mitogenic factor for gastrointestinal epithelial cells. Gastrin has two biologically active peptide forms, G34 and G17. [provided by RefSeq, Jul 2008]
uniprot summary :
gastrin: Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine. Belongs to the gastrin/cholecystokinin family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 17q21. Cellular Component: extracellular region. Molecular Function: protein binding; hormone activity. Biological Process: G-protein coupled receptor protein signaling pathway; signal transduction