catalog number :
MBS2018578
products type :
Recombinant Protein
products full name :
Recombinant Angiopoietin Like Protein 8 (ANGPTL8)
products short name :
Angiopoietin Like Protein 8 (ANGPTL8)
other names :
betatrophin; Betatrophin; betatrophin; lipasin; angiopoietin-like protein 8; hepatocellular carcinoma-associated gene TD26; hepatocellular carcinoma-associated protein TD26; chromosome 19 open reading frame 80; Angiopoietin-like protein 8; Lipasin
products gene name :
ANGPTL8
other gene names :
C19orf80; C19orf80; RIFL; TD26; ANGPTL8; PRO1185; PVPA599; Angptl8
uniprot entry name :
BETAT_HUMAN
form :
20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5%Trehalose and Proclin300.
storage stability :
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months. Stability Test : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed.The loss rate is less than 5% within the expiration date under appropriate storage condition.
tested application :
SDS-PAGE; WB; ELISA; IP; CoIP; Purification; Amine Reactive Labeling. (May be suitable for use in other assays to be determined by the end user.)
other info1 :
Source: Prokaryotic expression. Residues: Met24~Leu196. Tags: N-terminal His-Tag. Tissue Specificity: Liver. Subcellular Location: Secreted. Traits: Freeze-dried powder.
other info2 :
Predicted isoelectric point: 7.3. Predicted Molecular Mass: 23.4kDa. Accurate Molecular Mass: 25kDa as determined by SDS-PAGE reducing conditions. Usage: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
ncbi acc num :
NP_061157.3
ncbi gb acc num :
NM_018687.6
uniprot summary :
EG624219: Hormone that specifically promotes pancreatic beta cell proliferation and beta cell mass expansion, thereby improving glucose tolerance. Promotes pancreatic beta cell proliferation without insulin resistance. Also acts as a blood lipid regulator by regulating serum triglyceride levels; possibly by promoting ANGPTL3 cleavage. In response to food intake. Interacts with ANGPTL3. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 19p13.2. Cellular Component: extracellular region. Molecular Function: protein binding; hormone activity. Biological Process: fat cell differentiation; regulation of lipid metabolic process; regulation of lipoprotein metabolic process; cell maturation; cellular lipid metabolic process