catalog number :
MBS2018509
products type :
Recombinant Protein
products full name :
Recombinant Caspase 11 (CASP11)
products short name :
[Caspase 11 (CASP11)]
other names :
[splicing factor, arginine/serine-rich 2, interacting protein; Protein Scaf11; splicing factor, arginine/serine-rich 2, interacting protein; serine/arginine-rich splicing factor 2, interacting protein; SR-related CTD-associated factor 11]
products gene name :
[CASP11]
other gene names :
[Scaf11; Scaf11; SIP1; CASP11; SRRP129; Sfrs2ip; Srsf2ip; AI462454; mKIAA3013; 1110061H03Rik; 2610510E10Rik]
uniprot entry name :
E9PZM7_MOUSE
form :
20mM Tris, 150mM NaCl, pH8.0, containing 0.01% SKL, 5% Trehalose.
concentration :
Original Concentration: 200 ug/mL
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store at 2-8ºC for one month. Aliquot and store at -80ºC for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition
tested application :
Positive Control; Immunogen; SDS/PAGE; WB. (May be suitable for use in other assays to be determined by the end user.)
image1 heading :
SDS-Page
other info1 :
Organism Species: Mus musculus (Mouse). Source: Prokaryotic expression. Residues: Arg969~Trp1165. Tags: N-terminal His Tag. Subcellular Location: Nucleus. Traits: Freeze/dried powder
other info2 :
Predicted isoelectric point: 10.0. Predicted Molecular Mass: 26.4kDa. Accurate Molecular Mass: 31kDa as determined by SDS/PAGE reducing conditions. Phenomenon explanation: The possible reasons that the actual band size differs from the predicted are as follows:. 1.Splice variants: Alternative splicing may create different sized proteins from the same gene. 2. Relative charge: The composition of amino acids may affects the charge of the protein. 3. Post/translational modification: Phosphorylation, glycosylation, methylation etc. 4. Post/translation cleavage: Many proteins are synthesized as pro/proteins, and then cleaved to give the active form. 5. Polymerization of the target protein: Dimerization, multimerization etc. Usage: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1/1.0 mg/mL. Do not vortex.
ncbi acc num :
NP_082424.2
ncbi gb acc num :
NM_028148.2
uniprot summary :
SFRS2IP: Plays a role in pre-mRNA alternative splicing by regulating spliceosome assembly. 2 isoforms of the human protein are produced by alternative splicing. Protein type: RNA-binding; RNA splicing; RNA processing. Cellular Component: nucleoplasm; nucleolus; nucleus. Biological Process: RNA splicing, via transesterification reactions; RNA splicing; spliceosome assembly