product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Intercellular Adhesion Molecule 4 (ICAM4)
catalog :
MBS2018237
quantity :
0.01 mg
price :
175 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS2018237
products type :
Recombinant Protein
products full name :
Recombinant Intercellular Adhesion Molecule 4 (ICAM4)
products short name :
Intercellular Adhesion Molecule 4 (ICAM4)
other names :
intercellular adhesion molecule 4 isoform 3; Intercellular adhesion molecule 4; intercellular adhesion molecule 4; CD242 antigen; LW blood group protein; Landsteiner-Wiener blood group antigen a; Landsteiner-Wiener blood group glycoprotein; intercellular adhesion molecule 4 (LW blood group); intercellular adhesion molecule 4 isoform 3 anitgen LWa; intercellular adhesion molecule 4 (Landsteiner-Wiener blood group); Landsteiner-Wiener blood group glycoprotein
products gene name :
ICAM4
other gene names :
ICAM4; ICAM4; LW; CD242; LW; ICAM-4
uniprot entry name :
ICAM4_HUMAN
host :
E Coli
sequence length :
272
sequence :
The target protein is fused with two N-terminal Tags, His-tag and T7-tag, its sequence is listed below. MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGS- MSPEFVAVQ PGKSVQLNCS NSCPQPQNSS LRTPLRQGKT LRGPGWVSYQ LLDVRAWSSL AHCLVTCAGK TRWATSRITA YKPPHSVILE PPVLKGRKYT LRCHVTQVFP VGYLVVTLRH GSRVIYSESL ERFTGLDLANVTLTYEFAAG PRDFWQPVIC HARLNLDGLV VRNSSAPITL MLAW
purity :
> 95%
form :
Supplied as lyophilized form in 20mM Tris, 500 mM NaCl, pH 8.0, containing 1mM EDTA, 1mM DTT, 0.1% sarcosyl, 5% trehalose, and preservative.
storage stability :
Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months. Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
tested application :
SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
other info1 :
Organism: Homo sapiens (Human). Expression System: Prokaryotic expression. Residues: Met52~Trp234 (Accession # Q14773) with two N-terminal Tags, His-tag and T7-tag. Subcellular Location: Cell membrane; Single-pass type I membrane protein. Secreted
other info2 :
Endotoxin Level: <1.0EU per 1ug (determined by the LAL method). Predicted Isoelectric Point: 10.1. Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4. Usage: Reconsitute in ddH2O
products description :
About the Marker: Effective Size Range: 10kDa to 70kDa. Protein bands: 10kDa, 14kDa, 18kDa, 22kDa, 26kDa, 33kDa, 44kDa and70kDa. Double intensity bands: The 26kDa, 18kDa, 10kDa bands are at doubleintensity to make location and size approximation of proteins of interestquick and easy. Ready-to-use: No need to heat, dilute or add reducing agents before use.
ncbi gi num :
85068578
ncbi acc num :
NP_001034221.1
ncbi gb acc num :
NM_001039132.2
uniprot acc num :
Q14773
ncbi mol weight :
23.9kDa
ncbi pathways :
Adaptive Immune System Pathway (366160); Extracellular Matrix Organization Pathway (576262); Immune System Pathway (106386); Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway (106413); Integrin Cell Surface Interactions Pathway (106110)
ncbi summary :
This gene encodes the Landsteiner-Wiener (LW) blood group antigen(s) that belongs to the immunoglobulin (Ig) superfamily, and that shares similarity with the intercellular adhesion molecule (ICAM) protein family. This ICAM protein contains 2 Ig-like C2-type domains and binds to the leukocyte adhesion LFA-1 protein. The molecular basis of the LW(A)/LW(B) blood group antigens is a single aa variation at position 100; Gln-100=LW(A) and Arg-100=LW(B). Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
uniprot summary :
ICAM4: ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM4 is also a ligand for alpha-4/beta-1 and alpha-V integrins. Belongs to the immunoglobulin superfamily. ICAM family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 19p13.2-cen. Disease: Blood Group System, Landsteiner-wiener
size1 :
0.01 mg
price1 :
175 USD
size2 :
0.05 mg
price2 :
370
size3 :
0.1 mg
price3 :
575
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
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