protein

Recombinant Peptidoglycan Recognition Protein 1 (PGLYRP1)

MBS2018225

0.01 mg

145 USD

Recombinant Protein

Recombinant Peptidoglycan Recognition Protein 1 (PGLYRP1)

[Peptidoglycan Recognition Protein 1 (PGLYRP1)]

[peptidoglycan recognition protein 1; Peptidoglycan recognition protein 1; peptidoglycan recognition protein 1; TNF superfamily, member 3 (LTB)-like (peptidoglycan recognition protein); peptidoglycan recognition protein 1; Peptidoglycan recognition protein short]

[PGLYRP1]

[PGLYRP1; PGLYRP1; PGRP; TAG7; PGRPS; PGLYRP; PGRP-S; TNFSF3L; PGLYRP; PGRP; TNFSF3L; PGRP-S]

PGRP1_HUMAN

E Coli

196

> 95%

Original Concentration: 200 ug/mL

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37°C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.

Positive Control (PC) ; Immunogen ; SDS-PAGE ; Western Blot (WB). (May be suitable for use in other assays to be determined by the end user.)

Sequence Information

SDS-Page

Organism Species: Mus musculus (Mouse). Source: Prokaryotic expression. Residues: Phe19~Glu182. Tags: N-terminal His-Tag. Subcellular Location: Secreted, Cytoplasm. Traits: Freeze-dried powder. Buffer formulation: 100mMNaHCO 3 , 500mMNaCl, pH8.3, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.

Predicted isoelectric point: 7.8. Predicted Molecular Mass: 22.5kDa . Accurate Molecular Mass: 20kDa as determined by SDS-PAGE reducing conditions. Usage: Reconstitute in 100mM NaHCO3, 500mM NaCl (pH8.3) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

4827036

NP_005082.1

NM_005091.2

O75594

PGLYRP1: Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram- negative bacteria, and has bacteriostatic activity towards Gram- negative bacteria. Plays a role in innate immunity. Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. Protein type: Receptor, misc.; Secreted; Apoptosis; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 19q13.2-q13.3. Cellular Component: extracellular region. Molecular Function: peptidoglycan receptor activity; peptidoglycan binding; zinc ion binding; N-acetylmuramoyl-L-alanine amidase activity. Biological Process: defense response to Gram-positive bacterium; negative regulation of natural killer cell differentiation during immune response; detection of bacterium; negative regulation of interferon-gamma production; negative regulation of inflammatory response; innate immune response; immune response; pattern recognition receptor signaling pathway; peptidoglycan catabolic process

0.01 mg

145 USD

0.05 mg

280

0.1 mg

435

0.2 mg

535

0.5 mg

1035

1 mg

1540