antibody

Polyclonal Antibody to Apolipoprotein C1 (APOC1)

MBS2018207

0.01 mg

105 USD

polyclonal

rabbit

nonconjugated

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

Antibody

Polyclonal Antibody to Apolipoprotein C1 (APOC1)

[Apolipoprotein C1 (APOC1)]

[apolipoprotein C-I; Apolipoprotein C-I; apolipoprotein C-I; apolipoprotein C-I; Apolipoprotein C1]

[APOC1]

[Apoc1; Apoc1; apo-CI; apoC-I; Apo-CIB; ApoC-IB; Apo-CI; ApoC-I]

Polyclonal

Rabbit

Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

1 mg/ml

Storage: Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP).

Western blotting: 0.5-2 ug/mL;1:500-2000. Immunohistochemistry: 5-20 ug/mL;1:50-200. Immunocytochemistry: 5-20 ug/mL;1:50-200. Optimal working dilutions must be determined by end user.

Western Blot (WB)

Immunohistochemistry (IHC)

Organism Species: Mus musculus (Mouse). Source: Polyclonal antibody preparation. Traits: Liquid. Immunogen: Recombinant APOC1 (Gly32~Ser88 (Accession # P34928)) expressed in E.coli

Conjugated Antibody: The APC conjugated antibody version of this item is also available as catalog #MBS2040125

158517825

NP_001103479.1

NM_001110009.2

P34928

Statin Pathway (198363)

This gene encodes a precursor plasma protein that is cleaved to yield a signal peptide and two alternatively processed mature peptides. The encoded protein, which is a component of chylomicrons, very low density lipoproteins and high density lipoproteins, transports lipids from the intestines to other locations in the body. This protein binds to free fatty acids preventing their uptake by cells. This protein is a cofactor for lecithin cholesterol acyltransferase, an enzyme that catalyzes the conversion of free cholesterol to cholesteryl esters. The encoded protein inhibits the activity of the cholesteryl ester transfer protein which promotes the exchange of neutral lipids between lipoproteins. In humans this gene is associated with risk of coronary artery disease and age-associated memory impairment. Mice lacking this gene demonstrate impaired memory. This gene is clustered with three other apolipoprotein genes on chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]

APOC1: Appears to modulate the interaction of APOE with beta- migrating VLDL and inhibit binding of beta-VLDL to the LDL receptor-related protein. Binds free fatty acids and reduces their intracellular esterification. Belongs to the apolipoprotein C1 family. Protein type: Endoplasmic reticulum; Inhibitor; Lipid-binding; Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 7 A3 7 9.94 cM. Cellular Component: extracellular region. Biological Process: cholesterol metabolic process; lipid transport; lipoprotein metabolic process; transport; triacylglycerol metabolic process

0.01 mg

105 USD

0.02 mg

125

0.05 mg

170

0.1 mg

210

0.2 mg

315

1 mg

745