catalog number :
MBS2017838
products full name :
Polyclonal Antibody to Von Willebrand Factor (vWF)
products short name :
[Von Willebrand Factor (vWF)]
other names :
[von Willebrand factor; von Willebrand factor; von Willebrand factor]
products gene name :
[vWF]
other gene names :
[VWF; VWF; F8VWF; vWF]
purity :
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
form :
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
concentration :
0.28 mg/ml
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
tested application :
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP).
app notes :
Western blotting: 0.5-2 ug/mL;1:140-560. Immunohistochemistry: 5-20 ug/mL;1:14-56. Immunocytochemistry: 5-20 ug/mL;1:14-56. Optimal working dilutions must be determined by end user.
image1 heading :
Western Blot (WB)
other info1 :
Organism Species: Sus scrofa-Porcine (Pig). Source: Polyclonal antibody preparation. Traits: Liquid. Immunogen: Recombinant vWF (Asp1167-Val1334) expressed in E.coli
other info2 :
Conjugated Antibody: The APC conjugated antibody version of this item is also available as catalog #MBS2048291
ncbi pathways :
Complement And Coagulation Cascades Pathway (84485); Complement And Coagulation Cascades Pathway (484); ECM-receptor Interaction Pathway (84480); ECM-receptor Interaction Pathway (479); Focal Adhesion Pathway (84479); Focal Adhesion Pathway (478); PI3K-Akt Signaling Pathway (692249); PI3K-Akt Signaling Pathway (692979); Platelet Activation Pathway (953739)
uniprot summary :
Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex, glycoprotein Ibalpha/IX/V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma ().