antibody

FITC-linked Antibody to Cathepsin G (CTSG)

MBS2017770

0.1 mg

265 USD

polyclonal

rabbit

FITC

human, mouse

western blot, ELISA, immunohistochemistry, immunocytochemistry

Antibody

FITC-linked Antibody to Cathepsin G (CTSG)

[Cathepsin G (CTSG)]

[cathepsin G preproprotein; Cathepsin G; cathepsin G; cathepsin G]

[CTSG]

[CTSG; CTSG; CG; CATG; CG]

CATG_HUMAN

Polyclonal

Rabbit

Mouse

255

N/AAntigen-specific Affinity Chromatography.

Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.

200ug/ml

Storage: Avoid repeated freeze/thaw cycles. Store a t 4 degree C for frequent use. Aliquot and store a t -20 degree C for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blot (WB), IF, ELISA.

Western blotting: 0.5-2ug/ml. Immunocytochemistry in formalin fixed cells: 5-20ug/ml. Immunohistochemistry in formalin fixed frozen section: 5-20ug/ml. Immunohistochemistry in paraffin section: 5-20ug/ml. Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml. Optimal working dilutions must be determined by end user.

Western Blot

Source: Antibody labeling

Label: FITC. Traits: Liquid. Immunogen: Recombinant Cathepsin G (CTSG)

FITC Antibody

4503149

NP_001902.1

NM_001911.2

P08311

28,837 Da

ACE Inhibitor Pathway (198763); Activation Of Matrix Metalloproteinases Pathway (576264); Amoebiasis Pathway (167324); Amoebiasis Pathway (167191); Degradation Of The Extracellular Matrix Pathway (576263); Extracellular Matrix Organization Pathway (576262); Lysosome Pathway (99052); Lysosome Pathway (96865); Metabolism Of Angiotensinogen To Angiotensins Pathway (685555); Metabolism Of Proteins Pathway (106230)

The protein encoded by this gene, a member of the peptidase S1 protein family, is found in azurophil granules of neutrophilic polymorphonuclear leukocytes. The encoded protease has a specificity similar to that of chymotrypsin C, and may participate in the killing and digestion of engulfed pathogens, and in connective tissue remodeling at sites of inflammation. In addition, the encoded protein is antimicrobial, with bacteriocidal activity against S. aureus and N. gonorrhoeae. Transcript variants utilizing alternative polyadenylation signals exist for this gene. [provided by RefSeq, Sep 2014]

CTSG: Serine protease with trypsin- and chymotrypsin-like specificity. Cleaves complement C3. Has antibacterial activity against the Gram-negative bacterium P.aeruginosa, antibacterial activity is inhibited by LPS from P.aeruginosa, Z-Gly-Leu-Phe- CH2Cl and phenylmethylsulfonyl fluoride. Belongs to the peptidase S1 family. Protein type: Protease; EC 3.4.21.20; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 14q11.2. Cellular Component: extracellular matrix; extracellular space; cell surface; extracellular region; plasma membrane; nucleus; secretory granule. Molecular Function: peptidase activity; heparin binding; serine-type endopeptidase activity. Biological Process: extracellular matrix disassembly; extracellular matrix organization and biogenesis; positive regulation of immune response; cellular protein metabolic process; response to lipopolysaccharide; protein processing; immune response; proteolysis; angiotensin maturation; defense response to fungus

0.1 mg

265 USD

0.2 mg

410

1 mg

985