catalog number :
MBS2017488
products full name :
FITC-linked Antibody to Granzyme M (GZMM)
products short name :
Granzyme M (GZMM)
products gene name :
GZMM
sequence :
The target protein is fused with N-terminal His-Tag and its sequence is listed below. MGHHHHHHSGSEF-IIGGR EVIPHSRPYM ASLQRNGSHL CGGVLVHPKW VLTAAHCLAQ RMAQLRLVLG LHTLDSPGLT FHIKAAIQHP RYKPVPALEN DLALLQLDGK VKPSRTIRPL ALPSKRQVVA AGTRCSMAGW GLTHQGGRLS RVLRELDLQV LDTRMCNNSR FWNGSLSPSM VCLAADSKDQ APCKGDSGGP LVCGKGRVLA RVLSFSSRVC TDIFKPPVAT AVAPYVSWIR KVTGRSA
specificity :
The antibody is a rabbit polyclonal antibody raised against GZMM. It has been selected for its ability to recognize GZMM in immunohistochemical staining and western blotting.
purity :
Affinity Chromatography
form :
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
storage stability :
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles. Note: As fluorescence can photobleach when exposed to light, so the antibody
must be protected from light.
tested application :
Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blot (WB)
app notes :
Western blotting: 1:100-400. Immunocytochemistry in formalin fixed cells: 1:100-500 Immunohistochemistry in formalin fixed frozen section: 1:100-500. Immunohistochemistry in paraffin section: 1:50-200. Enzyme-linked Immunosorbent Assay: 1:100-200. Optimal working dilutions must be determined by end user.
products categories :
FITC Antibody
ncbi acc num :
BAA78336.1
uniprot summary :
GZMM: Cleaves peptide substrates after methionine, leucine, and norleucine. Physiological substrates include EZR, alpha- tubulins and the apoptosis inhibitor BIRC5/Survivin. Promotes caspase activation and subsequent apoptosis of target cells. Belongs to the peptidase S1 family. Granzyme subfamily. Protein type: Secreted, signal peptide; EC 3.4.21.-; Protease; Secreted. Cellular Component: membrane. Molecular Function: protein binding; serine-type peptidase activity; serine-type endopeptidase activity; endopeptidase activity. Biological Process: cell death; cytolysis; proteolysis