FITC-linked Antibody to Thyrotropin Releasing Hormone (TRH) | MyBioSource MBS2016918 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

FITC-linked Antibody to Thyrotropin Releasing Hormone (TRH)

catalog :

MBS2016918

quantity :

0.1 mg

price :

250 USD

clonality :

polyclonal

host :

rabbit

conjugate :

FITC

reactivity :

human, mouse

application :

immunohistochemistry, immunocytochemistry

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS2016918

products type :

Antibody

products full name :

FITC-linked Antibody to Thyrotropin Releasing Hormone (TRH)

products short name :

[Thyrotropin Releasing Hormone (TRH)]

other names :

[thyrotropin releasing hormone preproprotein; Pro-thyrotropin-releasing hormone; thyrotropin releasing hormone; protirelin; prothyroliberin; TSH-releasing factor; thyrotropin-releasing factor; pro-thyrotropin-releasing hormone; thyrotropin-releasing hormone; ProthyroliberinCleaved into the following chain:Thyrotropin-releasing hormone; TRH; Alternative name(s):; Protirelin; TSH-releasing factor; Thyroliberin; Thyrotropin-releasing factor]

products gene name :

[TRH]

other gene names :

[TRH; TRH; TRF; Pro-TRH; Pro-TRH; TRH; TRF]

clonality :

Polyclonal

host :

Rabbit

reactivity :

Mouse

sequence :

QHP

purity :

Antigen-specific Affinity Chromatography

form :

Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol

concentration :

200ug/ml

storage stability :

Storage: Avoid repeated freeze/thaw cycles. Store at 4°C for frequent use. Aliquot and store at -20°C for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. Note: As fluorescence can photobleach when exposed to light, so the antibody must be protected from light.

tested application :

IHC; ICC; IF

app notes :

Immunohistochemistry: 5-20µg/mL. Immunocytochemistry: 5-20µg/mL. Optimal working dilutions must be determined by end user

other info1 :

Source: Antibody labeling. Label: FITC. Traits: Liquid. Immunogen: Synthetic Peptide, TRH conjugated to OVA.

other info2 :

Unconjugated Antibody: The unconjugated antibody version of this item is also available as catalog #MBS2005590

products categories :

FITC Antibody

ncbi gi num :

6005920

ncbi acc num :

NP_009048.1

ncbi gb acc num :

NM_007117.4

uniprot acc num :

P20396

ncbi pathways :

Class A/1 (Rhodopsin-like Receptors) Pathway (106357); G Alpha (q) Signalling Events Pathway (106043); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); Gastrin-CREB Signalling Pathway Via PKC And MAPK (645295); Peptide Ligand-binding Receptors Pathway (106358); Signal Transduction Pathway (477114); Signaling By GPCR Pathway (106356); Thyroxine (Thyroid Hormone) Production Pathway (920992)

ncbi summary :

This gene encodes a member of the thyrotropin-releasing hormone family. Cleavage of the encoded proprotein releases mature thyrotropin-releasing hormone, which is a tripeptide hypothalamic regulatory hormone. The human proprotein contains six thyrotropin-releasing hormone tripeptides. Thyrotropin-releasing hormone is involved in the regulation and release of thyroid-stimulating hormone, as well as prolactin. Deficiency of this hormone has been associated with hypothalamic hypothyroidism. [provided by RefSeq, May 2013]

uniprot summary :

TRH: Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems. May promote hair shaft elongation, prolonge the hair cycle growth phase (anagen) and antagonized its termination by TGFB2. May also increase proliferation and inhibited apoptosis of hair matrix keratinocytes. Belongs to the TRH family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 3q13.3-q21. Cellular Component: extracellular region; plasma membrane; nucleus; secretory granule. Molecular Function: neuropeptide hormone activity; thyrotropin-releasing hormone activity. Biological Process: hormone-mediated signaling; negative regulation of glutamate secretion; eating behavior; positive regulation of insulin secretion; histamine metabolic process; signal transduction; adult walking behavior; response to ethanol; cell-cell signaling; response to hypoxia; response to glucose stimulus; response to cold; response to corticosterone stimulus; positive regulation of gamma-aminobutyric acid secretion. Disease: Thyrotropin-releasing Hormone Deficiency

size1 :

0.1 mg

price1 :

250 USD

size2 :

0.2 mg

price2 :

375

size3 :

1 mg

price3 :

885

more info or order :

MyBioSource product webpage