catalog number :
MBS2016496
products full name :
FITC-linked Antibody to Microtubule Associated Protein 2 (MAP2)
products short name :
Microtubule Associated Protein 2 (MAP2)
other names :
microtubule associated protein 2, partial; Microtubule-associated protein 2; microtubule-associated protein 2; MAP-2; microtubule-associated protein 2
products gene name :
MAP2
other gene names :
MAP2; MAP2; MAP2A; MAP2B; MAP2C; MAP-2
uniprot entry name :
MTAP2_HUMAN
specificity :
The antibody is a rabbit polyclonal antibody raised against MAP2 conjugated to fitc. It has been selected for its ability to recognize MAP2 in immunohistochemical staining andwestern blotting.
purity :
Affinity Chromatography
form :
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.
storage stability :
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
tested application :
Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blot (WB)
app notes :
Western blotting: 1:100-400. Immunocytochemistry in formalin fixed cells: 1:100-500. Immunohistochemistry in formalin fixed frozen section: 1:100-500. Immunohistochemistry in paraffin section: 1:50-200. Enzyme-linked Immunosorbent Assay: 1:100-200
other info2 :
Conjugation: FITC
products categories :
FITC Antibody
ncbi acc num :
AAA59552.1
ncbi mol weight :
199,526 Da
ncbi pathways :
LKB1 Signaling Events Pathway (137957); MAPK Cascade Pathway (198834); SIDS Susceptibility Pathways (198901)
ncbi summary :
This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jan 2010]
uniprot summary :
MAP2: a member of the microtubule-associated protein (MAP) family. Its exact function is unknown but MAPs appear to stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules. Expressed at high levels in neural tissue and the prostate. Four alternatively spliced transcript variants have been reported. Protein type: Motility/polarity/chemotaxis; Cytoskeletal. Chromosomal Location of Human Ortholog: 2q34-q35. Cellular Component: microtubule; microtubule associated complex; cell soma; cytoplasm; nucleolus; dendritic shaft. Molecular Function: calmodulin binding; protein binding; microtubule binding; structural molecule activity. Biological Process: axonogenesis; dendrite morphogenesis; neurite development; microtubule bundle formation; central nervous system neuron development