catalog number :
MBS2016453
products full name :
FITC-linked Antibody to Defensin Beta 1 (DEFb1)
products short name :
Defensin Beta 1 (DEFb1)
other names :
defensin, beta 1; Beta-defensin 1; beta-defensin 1; BD-1; beta-defensin-1; defensin, beta 1; Defensin, beta 1
products gene name :
DEFb1
other gene names :
DEFB1; DEFB1; BD1; HBD1; DEFB-1; DEFB101; BD1; HBD1; BD-1; hBD-1
uniprot entry name :
DEFB1_HUMAN
specificity :
The antibody is a rabbit polyclonal antibody raised against DEFb1 conjugated to fitc. It has been selected for its ability to recognize DEFb1 in immunohistochemical staining andwestern blotting.
purity :
Antigen-specific Affinity Chromatography.
form :
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed.The loss rate is less than 5% within the expiration date under appropriate storage condition. Note: As fluorescence can photobleach when exposed to light, so the antibody must be protected from light.
tested application :
WB; ICC; IHC-P; IHC-F; ELISA, Flow Cyt.
app notes :
Western blotting: 0.5-2ug/ml. Immunocytochemistry in formalin fixed cells: 5-20ug/ml. Immunohistochemistry in formalin fixed frozen section: 5-20ug/ml. Immunohistochemistry in paraffin section: 5-20ug/ml. Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml. Optimal working dilutions must be determined by end user.
other info1 :
Source: Antibody labeling. Label: FITC. Traits: Liquid. Immunogen: Recombinant DEFb1 (Asn24~Lys64) expressed in E.coli.
products categories :
FITC Antibody
ncbi acc num :
EAW80482.1
ncbi pathways :
Beta Defensins Pathway (530759); Defensins Pathway (530757); Immune System Pathway (106386); Innate Immune System Pathway (106387)
ncbi summary :
Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis. [provided by RefSeq, Jul 2008]
uniprot summary :
defensin, beta 1: Has bactericidal activity. Belongs to the beta-defensin family. Protein type: Motility/polarity/chemotaxis; Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 8p23.1. Cellular Component: extracellular space; Golgi lumen; extracellular region. Biological Process: G-protein coupled receptor protein signaling pathway; defense response to Gram-positive bacterium; innate immune response in mucosa; response to bacterium; antibacterial humoral response; innate immune response; immune response; response to testosterone stimulus; chemotaxis; acute inflammatory response