Biotin-Linked Antibody to Protein Tyrosine Phosphatase Receptor Type S (PTPRS) | MyBioSource MBS2015751 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Biotin-Linked Antibody to Protein Tyrosine Phosphatase Receptor Type S (PTPRS)

catalog :

MBS2015751

quantity :

0.1 mg

price :

380 USD

clonality :

polyclonal

host :

rabbit

conjugate :

biotin

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, enzyme immunoassay, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS2015751

products type :

Antibody

products full name :

Biotin-Linked Antibody to Protein Tyrosine Phosphatase Receptor Type S (PTPRS)

products short name :

Protein Tyrosine Phosphatase Receptor Type S (PTPRS)

other names :

protein tyrosine phosphatase, receptor type, S, isoform CRA_h; Receptor-type tyrosine-protein phosphatase S; receptor-type tyrosine-protein phosphatase S; R-PTP-S; R-PTP-sigma; protein tyrosine phosphatase PTPsigma; receptor-type tyrosine-protein phosphatase sigma; protein tyrosine phosphatase, receptor type, sigma; protein tyrosine phosphatase, receptor type, S; Receptor-type tyrosine-protein phosphatase sigma

products gene name :

PTPRS

other gene names :

PTPRS; PTPRS; PTPSIGMA; R-PTP-S; R-PTP-sigma

uniprot entry name :

PTPRS_HUMAN

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Mouse

sequence length :

1910

sequence :

The target protein is fused with two N-terminal Tags, His-tag and T7-tag and its sequence is listed below. MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- RT KCLLNNADLA PHHPKDPVEM RRINFQTPGM LSHPPIPITD MAEHMERLKA NDSLKLSQEY ESIDPGQQFT WEHSNLEANK PKNRYANVIA YDHSRVILQP LEGIMGSDYI NANYVDGYRR QNAYIATQGP LPETFGDFWR MVWEQRSATV VMMTRLEEKS RIKCDQYWPN RGTETYGFIQ VTLLDTMELA TFCVRTFSLH KNGSSEKREV RH

specificity :

The antibody is a rabbit polyclonal antibody raised against PTPRS. It has been selected for its ability to recognize PTPRS in immunohistochemical staining and western blotting.

purity :

Affinity Chromatography

form :

Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.

concentration :

200ug/ml

storage stability :

Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

tested application :

Immunohistochemistry (IHC)/(IHC-P)/(IHC-F), ELISA (EIA), Western Blot (WB), (ICC)

app notes :

Western blotting: 1: 100-400 . Immunocytochemistry in formalin fixed cells: 1:100-500. Immunohistochemistry in formalin fixed frozen section: 1: 1 00-500. Immunohistochemistry in paraffin section: 1 :50-200. Enzyme-linked Immunosorbent Assay: 1: 1 00-200. Optimal working dilutions must be determined by end user.

other info1 :

Accession No.: RPB295Mu01

products categories :

Biotin Antibody

ncbi gi num :

119589584

ncbi acc num :

EAW69178.1

uniprot acc num :

Q13332

ncbi mol weight :

217,041 Da

ncbi pathways :

ECM Proteoglycans Pathway (833812); Extracellular Matrix Organization Pathway (576262)

ncbi summary :

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of multiple Ig-like and fibronectin type III-like domains. Studies of the similar gene in mice suggested that this PTP may be involved in cell-cell interaction, primary axonogenesis, and axon guidance during embryogenesis. This PTP has been also implicated in the molecular control of adult nerve repair. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008]

uniprot summary :

PTPRS: Interacts with LAR-interacting protein LIP.1. Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily. 7 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral; EC 3.1.3.48; Motility/polarity/chemotaxis; Receptor protein phosphatase, tyrosine. Chromosomal Location of Human Ortholog: 19p13.3. Cellular Component: integral to plasma membrane. Molecular Function: protein binding; transmembrane receptor protein tyrosine phosphatase activity. Biological Process: corpus callosum development; extracellular matrix organization and biogenesis; spinal cord development; hippocampus development; cerebellum development; cerebral cortex development; cell adhesion

size1 :

0.1 mg

price1 :

380 USD

more info or order :

MyBioSource product webpage