catalog number :
MBS2014105
products full name :
FITC-linked Antibody to Periostin (POSTN)
products short name :
[Periostin (POSTN)]
other names :
[periostin isoform 1; Periostin; periostin; periodontal ligament-specific periostin; osteoblast specific factor 2 (fasciclin I-like); periostin, osteoblast specific factor; Osteoblast-specific factor 2]
products gene name :
[POSTN]
other gene names :
[POSTN; POSTN; PN; OSF2; OSF-2; PDLPOSTN; periostin; OSF2; PN; OSF-2]
uniprot entry name :
POSTN_HUMAN
purity :
Antigen-specific Affinity Chromatography.
form :
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store at 4°C for frequent use. Aliquot and store at -20°C for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. Note: As fluorescence can photobleach when exposed to light, so the antibody must be protected from light.
tested application :
Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blot (WB)
app notes :
Western blotting: 0.5-2ug/mL. Immunohistochemistry: 5-20ug/mL. Immunocytochemistry: 5-20ug/mL. Optimal working dilutions must be determined by end user.
other info1 :
Source: Antibody labeling. Label: FITC. Traits: Liquid
other info2 :
Immunogen: Recombinant POSTN (Ser500-Leu630) expressed in E.cali.
products categories :
FITC Antibody
ncbi acc num :
NP_006466.2
ncbi gb acc num :
NM_006475.2
ncbi summary :
This gene encodes a secreted extracellular matrix protein that functions in tissue development and regeneration, including wound healing, and ventricular remodeling following myocardial infarction. The encoded protein binds to integrins to support adhesion and migration of epithelial cells. This protein plays a role in cancer stem cell maintenance and metastasis. Mice lacking this gene exhibit cardiac valve disease, and skeletal and dental defects. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015]
uniprot summary :
POSTN: Binds to heparin. Induces cell attachment and spreading and plays a role in cell adhesion. May play a role in extracellular matrix mineralization. 4 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted; Motility/polarity/chemotaxis; Cell adhesion; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 13q13.3. Cellular Component: extracellular matrix; extracellular space; proteinaceous extracellular matrix; trans-Golgi network. Molecular Function: heparin binding; protein binding; cell adhesion molecule binding. Biological Process: tissue development; extracellular matrix organization and biogenesis; regulation of Notch signaling pathway; cell adhesion; skeletal development