FITC-linked Antibody to Carnitine Palmitoyltransferase 1A, Liver (CPT1A) | MyBioSource MBS2013969 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

FITC-linked Antibody to Carnitine Palmitoyltransferase 1A, Liver (CPT1A)

catalog :

MBS2013969

quantity :

0.1 mg

price :

260 USD

clonality :

polyclonal

host :

rabbit

conjugate :

FITC

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS2013969

products type :

Antibody

products full name :

FITC-linked Antibody to Carnitine Palmitoyltransferase 1A, Liver (CPT1A)

products short name :

[Carnitine Palmitoyltransferase 1A, Liver (CPT1A)]

other names :

[carnitine palmitoyltransferase 1A (liver), isoform CRA_a; Carnitine O-palmitoyltransferase 1, liver isoform; carnitine O-palmitoyltransferase 1, liver isoform; CPT I; CPTI-L; carnitine palmitoyltransferase I, liver; carnitine O-palmitoyltransferase I, liver isoform; carnitine palmitoyltransferase 1A (liver); Carnitine O-palmitoyltransferase I, liver isoform; CPT I; CPTI-L; Carnitine palmitoyltransferase 1A]

products gene name :

[CPT1A]

other gene names :

[CPT1A; CPT1A; CPT1; CPT1-L; L-CPT1; CPT1; CPT1-L; CPT I; CPTI-L]

uniprot entry name :

CPT1A_HUMAN

clonality :

Polyclonal

host :

Rabbit

purity :

Antigen-specific Affinity Chromatography

form :

Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

concentration :

200ug/ml

storage stability :

Storage : Avoid repeated freeze/thaw cycles. Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 24 months. Stability Test : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. Note : As fluorescence can photobleach when exposed to light, so the antibody must be protected from light.

tested application :

WB; ICC; IHC; IF

app notes :

Western blotting: 0.5-2ug/ml. Immunocytochemistry: 5-20ug/ml. Immunohistochemistry: 5-20ug/ml. Optimal working dilutions must be determined by end user.

other info1 :

Source: Antibody labeling. Label: FITC. Traits: Liquid. Immunogen: Recombinant CPT1A (Arg191~Leu353) expressed in E.coli.

other info2 :

Species: Human

products categories :

FITC Antibody

ncbi gi num :

119595128

ncbi acc num :

EAW74722.1

uniprot acc num :

P50416

ncbi pathways :

AMPK Signaling Pathway (198868); Adipocytokine Signaling Pathway (83093); Adipocytokine Signaling Pathway (505); Circadian Clock Pathway (187173); FOXA2 And FOXA3 Transcription Factor Networks Pathway (137911); Fatty Acid Beta Oxidation Pathway (198865); Fatty Acid Degradation Pathway (82935); Fatty Acid Degradation Pathway (296); Fatty Acid Metabolism Pathway (868084); Fatty Acid Metabolism Pathway (878045)

ncbi summary :

The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

uniprot summary :

CPT1A: Belongs to the carnitine/choline acetyltransferase family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, multi-pass; Mitochondrial; Membrane protein, integral; EC 2.3.1.21; Lipid Metabolism - fatty acid; Transferase. Chromosomal Location of Human Ortholog: 11q13.2. Cellular Component: mitochondrial outer membrane; membrane; mitochondrion; mitochondrial inner membrane; integral to mitochondrial outer membrane. Molecular Function: identical protein binding; carnitine O-palmitoyltransferase activity. Biological Process: response to drug; circadian rhythm; eating behavior; glucose metabolic process; carnitine shuttle; cellular lipid metabolic process; long-chain fatty acid metabolic process; response to organic cyclic substance; positive regulation of fatty acid beta-oxidation; triacylglycerol metabolic process; fatty acid beta-oxidation; epithelial cell differentiation; carnitine metabolic process; regulation of insulin secretion; protein homooligomerization. Disease: Carnitine Palmitoyltransferase I Deficiency

size1 :

0.1 mg

price1 :

260 USD

size2 :

0.2 mg

price2 :

400

size3 :

1 mg

price3 :

955

more info or order :

MyBioSource product webpage