FITC-linked Antibody to Interleukin 10 Receptor Beta (IL10Rb) | MyBioSource MBS2013838 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

FITC-linked Antibody to Interleukin 10 Receptor Beta (IL10Rb)

catalog :

MBS2013838

quantity :

0.1 mg

price :

255 USD

clonality :

polyclonal

host :

rabbit

conjugate :

FITC

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS2013838

products type :

Antibody

products full name :

FITC-linked Antibody to Interleukin 10 Receptor Beta (IL10Rb)

products short name :

[Interleukin 10 Receptor Beta (IL10Rb)]

other names :

[interleukin 10 beta receptor; Interleukin-10 receptor subunit beta; interleukin-10 receptor subunit beta; IL-10RB; IL-10R subunit 2; IL-10R subunit beta; IL-10 receptor subunit beta; cytokine receptor class-II CRF2-4; interleukin-10 receptor subunit 2; cytokine receptor class-II member 4; cytokine receptor family 2 member 4; cytokine receptor family II, member 4; interleukin 10 receptor, beta; Cytokine receptor class-II member 4; Cytokine receptor family 2 member 4; CRF2-4; Interleukin-10 receptor subunit 2]

products gene name :

[IL10Rb]

other gene names :

[IL10RB; IL10RB; CRFB4; CRF2-4; D21S58; D21S66; CDW210B; IL-10R2; CRFB4; D21S58; D21S66; IL-10 receptor subunit beta; IL-10R subunit beta; IL-10RB; CRF2-4; IL-10R subunit 2; IL-10R2]

uniprot entry name :

I10R2_HUMAN

clonality :

Polyclonal

host :

Rabbit

reactivity :

Mouse

purity :

Antigen-specific affinity chromatography

form :

Supplied as solution form in 0.01m PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol

concentration :

200ug/ml

storage stability :

Storage: Avoid repeated freeze-thaw cycles. Store at 4°C for frequent use. Aliquot and store at -20°C for 12 months. Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. Note: As fluorescence can photobleach when exposed to light, so the antibody must be protected from light.

tested application :

WB; IHC; ICC; IF

app notes :

Western blotting: 0.5-2µg/mL. Immunohistochemistry: 5-20µg/mL. Immunocytochemistry: 5-20µg/mL. Optimal working dilutions must be determined by end user

other info1 :

Source: Antibody labeling. Label: FITC. Traits: Liquid. Immunogen: Recombinant IL10Rb (Val42~Thr218) expressed in E.coli

products categories :

FITC Antibody

ncbi gi num :

371941988

ncbi acc num :

AEX60807.1

uniprot acc num :

Q08334

ncbi pathways :

Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Epstein-Barr Virus Infection Pathway (585562); Epstein-Barr Virus Infection Pathway (587115); Jak-STAT Signaling Pathway (83077); Jak-STAT Signaling Pathway (488); Toxoplasmosis Pathway (169642); Toxoplasmosis Pathway (169493); Tuberculosis Pathway (213780); Tuberculosis Pathway (213743)

ncbi summary :

The protein encoded by this gene belongs to the cytokine receptor family. It is an accessory chain essential for the active interleukin 10 receptor complex. Coexpression of this and IL10RA proteins has been shown to be required for IL10-induced signal transduction. This gene and three other interferon receptor genes, IFAR2, IFNAR1, and IFNGR2, form a class II cytokine receptor gene cluster located in a small region on chromosome 21. [provided by RefSeq, Jul 2008]

uniprot summary :

IL10RB: Shared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IL29. Defects in IL10RB are the cause of inflammatory bowel disease type 25 (IBD25). It is a chronic, relapsing inflammation of the gastrointestinal tract with a complex etiology. It is subdivided into Crohn disease and ulcerative colitis phenotypes. Crohn disease may affect any part of the gastrointestinal tract from the mouth to the anus, but most frequently it involves the terminal ileum and colon. Bowel inflammation is transmural and discontinuous; it may contain granulomas or be associated with intestinal or perianal fistulas. In contrast, in ulcerative colitis, the inflammation is continuous and limited to rectal and colonic mucosal layers; fistulas and granulomas are not observed. Both diseases include extraintestinal inflammation of the skin, eyes, or joints. Belongs to the type II cytokine receptor family. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 21q22.11. Cellular Component: integral to membrane; plasma membrane; interleukin-28 receptor complex. Molecular Function: protein binding; interleukin-10 receptor activity; receptor activity. Biological Process: cytokine and chemokine mediated signaling pathway; immune response; signal transduction; inflammatory response; defense response to virus. Disease: Inflammatory Bowel Disease 25, Autosomal Recessive; Hepatitis B Virus, Susceptibility To

size1 :

0.1 mg

price1 :

255 USD

size2 :

0.2 mg

price2 :

390

size3 :

1 mg

price3 :

935

more info or order :

MyBioSource product webpage