FITC-linked Antibody to Glycoprotein 130 (gp130) | MyBioSource MBS2013571 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

FITC-linked Antibody to Glycoprotein 130 (gp130)

catalog :

MBS2013571

quantity :

0.1 mg

price :

385 USD

clonality :

polyclonal

host :

rabbit

conjugate :

FITC

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS2013571

products type :

Antibody

products full name :

FITC-linked Antibody to Glycoprotein 130 (gp130)

products short name :

Glycoprotein 130 (gp130)

other names :

glycoprotein 130; Interleukin-6 receptor subunit beta; interleukin-6 receptor subunit beta; IL-6RB; IL-6R-beta; IL-6R subunit beta; membrane glycoprotein 130; IL-6 receptor subunit beta; interleukin-6 signal transducer; oncostatin-M receptor subunit alpha; interleukin 6 signal transducer; Interleukin-6 signal transducer; Membrane glycoprotein 130; gp130; Oncostatin-M receptor subunit alpha

products gene name :

gp130

other gene names :

Il6st; Il6st; CD130; gp130; AA389424; BB405851; D13Ertd699e; 5133400A03Rik; IL-6 receptor subunit beta; IL-6R subunit beta; IL-6R-beta; IL-6RB; gp130

uniprot entry name :

IL6RB_MOUSE

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Human

sequence length :

917

specificity :

The antibody is a rabbit polyclonal antibody raised against gp130. It has been selected for its ability to recognize gp130 in immunohistochemical staining and western blotting.

purity :

Affinity Chromatography

form :

Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.

concentration :

100ug/ml

storage stability :

Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles. Note: As fluorescence can photobleach when exposed to light, so the antibody must be protected from light.

tested application :

Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blot (WB)

app notes :

Western blotting: 1:50-400. Immunocytochemistry in formalin fixed cells: 1:50-500. Immunohistochemistry in formalin fixed frozen section: 1:50-500. Immunohistochemistry in paraffin section: 1:10-100. Enzyme-linked Immunosorbent Assay: 1:100-200. Optimal working dilutions must be determined by end user.

products categories :

FITC Antibody

ncbi gi num :

193592

ncbi acc num :

AAA37723.1

uniprot acc num :

Q00560

ncbi mol weight :

102,451 Da

ncbi pathways :

Adipogenesis Pathway (198299); Androgen Receptor Signaling Pathway (198319); Cytokine Signaling In Immune System Pathway (926145); Cytokine-cytokine Receptor Interaction Pathway (83248); Cytokine-cytokine Receptor Interaction Pathway (460); ESC Pluripotency Pathways (198374); IL-6 Signaling Pathway (198302); Immune System Pathway (926012); Interleukin-6 Signaling Pathway (926160); Jak-STAT Signaling Pathway (83274)

uniprot summary :

gp130: gp130 is a ubiquitously expressed type I cytokine family receptor. The receptor systems for IL6, LIF, OSM, CNTF, IL11 AND CT1 utilize gp130 for initiating signal transmission. Binds to IL6/IL6R (alpha chain) complex, resulting in the formation of high-affinity IL6 binding sites, and transduces the signal. Does not directly bind IL6. May have a role in embryonic development. Contains 5 fibronectin type III domains and 1 immunoglobulin-like C2-type domain. Two alternatively spliced isoforms have been described. Protein type: Membrane protein, integral; Receptor, cytokine. Cellular Component: extracellular space; cell soma; membrane; oncostatin-M receptor complex; dendrite; integral to membrane; interleukin-6 receptor complex; cytosol; external side of plasma membrane. Molecular Function: hematopoietin/interferon-class (D200-domain) cytokine receptor activity; interleukin-11 binding; protein binding; interleukin-6 binding; interleukin-6 receptor binding; leukemia inhibitory factor receptor activity; oncostatin-M receptor activity; protein heterodimerization activity; growth factor binding; ciliary neurotrophic factor receptor activity; interleukin-6 receptor activity; ciliary neurotrophic factor receptor binding; interleukin-11 receptor activity. Biological Process: glycogen metabolic process; cytokine and chemokine mediated signaling pathway; leukemia inhibitory factor signaling pathway; positive regulation of smooth muscle cell migration; signal transduction; positive regulation of tyrosine phosphorylation of Stat3 protein; positive regulation of osteoblast differentiation; positive regulation of tyrosine phosphorylation of Stat1 protein; regulation of Notch signaling pathway; response to cytokine stimulus; reduction of cytosolic calcium ion concentration; positive regulation of cell proliferation; positive regulation of T cell proliferation; triacylglycerol mobilization; positive regulation of astrocyte differentiation

size1 :

0.1 mg

price1 :

385 USD

more info or order :

MyBioSource product webpage