product summary
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company name :
MyBioSource
product type :
antibody
product name :
FITC-linked Antibody to Glutathione (GSH)
catalog :
MBS2013376
quantity :
0.1 mg
price :
375 USD
clonality :
polyclonal
host :
rabbit
conjugate :
FITC
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS2013376
products type :
Antibody
products full name :
FITC-linked Antibody to Glutathione (GSH)
products short name :
Glutathione (GSH)
other names :
glutathione S-transferase Mu 2 isoform 2; Glutathione S-transferase Mu 2; glutathione S-transferase Mu 2; GST, muscle; GST class-mu 2; glutathione S-transferase 4; glutathione S-transferase M1; glutathione S-aryltransferase M2; glutathione S-alkyltransferase M2; glutathione S-aralkyltransferase M2; S-(hydroxyalkyl)glutathione lyase M2; glutathione S-transferase M2 (muscle); glutathione S-transferase mu 2 (muscle); GST class-mu 2; GSTM2-2
products gene name :
GSH
other gene names :
GSTM2; GSTM2; GST4; GSTM; GTHMUS; GSTM2-2; GST4
uniprot entry name :
GSTM2_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
General
sequence length :
191
specificity :
The antibody is a rabbit polyclonal antibody raised against GSH. It has been selected for its ability to recognize GSH in immunohistochemical staining and western blotting.
purity :
Affinity Chromatography
form :
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
concentration :
200ug/ml
storage stability :
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
tested application :
Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blot (WB), ELISA
app notes :
Western blotting: 1:50-400. Immunocytochemistry in formalin fixed cells: 1:50-500. Immunohistochemistry in formalin fixed frozen section: 1:50-500. Immunohistochemistry in paraffin section: 1:10-100. Enzyme-linked Immunosorbent Assay: 1:100-1:5000. Optimal working dilutions must be determined by end user.
other info1 :
Immunogen: GSH-OVA. Conjugation: FITC. Immunogen Information: Small Molecule, GSH conjugated to OVA. Accession No.: CPA294Ge21. Chemical Formula: C10H17N3O6S. Mol. Mass: 307.3g/mol
products categories :
FITC Antibody
ncbi gi num :
215277000
ncbi acc num :
NP_001135840.1
ncbi gb acc num :
NM_001142368.1
uniprot acc num :
P28161
ncbi mol weight :
25,745 Da
ncbi pathways :
Biological Oxidations Pathway (105698); Chemical Carcinogenesis Pathway (673221); Chemical Carcinogenesis Pathway (673237); Drug Metabolism - Cytochrome P450 Pathway (83032); Drug Metabolism - Cytochrome P450 Pathway (427); Glutathione Conjugation Pathway (105727); Glutathione Metabolism Pathway (82973); Glutathione Metabolism Pathway (198824); Glutathione Metabolism Pathway (343); Metabolism Pathway (477135)
ncbi summary :
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. [provided by RefSeq, Jul 2008]
uniprot summary :
GSTM2: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Belongs to the GST superfamily. Mu family. Protein type: Transferase; Motility/polarity/chemotaxis; EC 2.5.1.18. Chromosomal Location of Human Ortholog: 1p13.3. Cellular Component: sarcoplasmic reticulum; cytoplasm; cytosol. Molecular Function: enzyme binding; protein homodimerization activity; glutathione binding; glutathione transferase activity; receptor binding. Biological Process: regulation of skeletal muscle contraction via regulation of the release of sequestered calcium ion; glutathione metabolic process; nitrobenzene metabolic process; xenobiotic metabolic process; xenobiotic catabolic process
size1 :
0.1 mg
price1 :
375 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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