catalog number :
MBS2012637
products full name :
Monoclonal Antibody to Cyclin D1 (CCND1)
products short name :
[Cyclin D1 (CCND1)]
other names :
[G1/S-specific cyclin-D1; G1/S-specific cyclin-D1; G1/S-specific cyclin-D1; cyclin D1]
products gene name :
[CCND1]
other gene names :
[CCND1; CCND1]
purity :
Protein A + Protein G affinity chromatography
form :
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
concentration :
0.29 mg/ml
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
tested application :
Western Blot (WB); Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP).
app notes :
Western blotting: 0.5-2 ug/mL;1:150-600. Immunohistochemistry: 5-20 ug/mL;1:15-60. Immunocytochemistry: 5-20 ug/mL;1:15-60. Optimal working dilutions must be determined by end user.
image1 heading :
Western Blot (WB)
other info1 :
Organism Species: Chicken (Gallus). Source: Monoclonal antibody preparation. Traits: Liquid. Immunogen: Recombinant CCND1 (Met1~Ile292 (Accession # P55169)) expressed in E.coli
other info2 :
Conjugated Antibody: The APC conjugated antibody version of this item is also available as catalog #MBS2044580
ncbi acc num :
NP_990712.1
ncbi gb acc num :
NM_205381.1
ncbi pathways :
Androgen Receptor Signaling Pathway (199072); Cell Cycle Pathway (83960); Cell Cycle Pathway (463); Focal Adhesion Pathway (119312); Focal Adhesion Pathway (478); G1 To S Cell Cycle Control Pathway (199055); Jak-STAT Signaling Pathway (83972); Jak-STAT Signaling Pathway (488); Wnt Signaling Pathway (199073); Wnt Signaling Pathway (83967)
uniprot summary :
Essential for the control of the cell cycle at the G1/S (start) transition. Interacts with the CDK4 and CDK6 protein kinases. May play a role in transcriptional regulation ().