catalog number :
MBS2012550
products full name :
Monoclonal Antibody to Insulin Like Growth Factor Binding Protein 5 (IGFBP5)
products short name :
[Insulin Like Growth Factor Binding Protein 5 (IGFBP5)]
other names :
[insulin-like growth factor-binding protein 5; Insulin-like growth factor-binding protein 5; insulin-like growth factor-binding protein 5; insulin like growth factor binding protein 5]
products gene name :
[IGFBP5]
other gene names :
[IGFBP5; IGFBP5; IBP5; IBP5; IBP-5; IGF-binding protein 5; IGFBP-5]
purity :
Protein A + Protein G affinity chromatography
form :
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
tested application :
Western Blot (WB), Immunohistochemistry (IHC),Immunocytochemistry (ICC),Immunoprecipitation (IP).
app notes :
Western blotting: 0.5-2 ug/mL;1:500-2000. Immunohistochemistry: 5-20 ug/mL;1:50-200. Immunocytochemistry: 5-20 ug/mL;1:50-200. Optimal working dilutions must be determined by end user
image1 heading :
Western Blot (WB)
other info1 :
Organism Species: Homo sapiens (Human). Source: Monoclonal antibody preparation. Traits: Liquid. Immunogen: Recombinant IGFBP5 (Cys27~Gly248 (Accession # P24593)) expressed in E.coli
ncbi acc num :
NP_000590.1
ncbi gb acc num :
NM_000599.3
ncbi pathways :
Metabolism Of Proteins Pathway (106230); Myometrial Relaxation And Contraction Pathways (198759); Regulation Of Insulin-like Growth Factor (IGF) Transport And Uptake By Insulin-like Growth Factor Binding Proteins (IGFBPs) Pathway (105908); Senescence And Autophagy Pathway (198780)
uniprot summary :
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.