Monoclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 14 (TNFSF14) | MyBioSource MBS2012494 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Monoclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 14 (TNFSF14)

catalog :

MBS2012494

quantity :

0.01 mg

price :

100 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

[C1]

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

MyBioSource product webpage

image

image 1 :

Western Blot: Sample: Human MCF7 cell lysate; Primary Ab: 2ug/ml Mouse Anti-Human HSPD1 Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody

image 2 :

Western Blot: Sample: Recombinant TNFSF14, Human.

product information

catalog number :

MBS2012494

products type :

Antibody

products full name :

Monoclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 14 (TNFSF14)

products short name :

[Tumor Necrosis Factor Ligand Superfamily, Member 14 (TNFSF14)]

other names :

[tumor necrosis factor ligand superfamily member 14 isoform 1; Tumor necrosis factor ligand superfamily member 14; tumor necrosis factor ligand superfamily member 14; TNF superfamily member 14; Herpes virus entry mediator ligand; HVEM-L; Herpesvirus entry mediator ligand]

products gene name :

[TNFSF14]

other gene names :

[TNFSF14; TNFSF14; LTg; CD258; HVEML; LIGHT; HVEML; LIGHT; HVEM-L; Herpesvirus entry mediator ligand]

clonality :

Monoclonal

isotype :

IgG1 Kappa

clone :

[C1]

host :

Mouse

purity :

Protein A + Protein G affinity chromatography

form :

Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

concentration :

1mg/ml

storage stability :

Storage: Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 12 months. <br?Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition

tested application :

Western Blot (WB); Immunohistochemistry (IHC); Immunocytochemistry (ICC);Immunoprecipitation (IP).

app notes :

Western blotting: 0.5-2 ug/mL;1:500-2000. Immunohistochemistry: 5-20 ug/mL;1:50-200. Immunocytochemistry: 5-20 ug/mL;1:50-200. Optimal working dilutions must be determined by end user

image1 heading :

Western Blot (WB)

image2 heading :

Western Blot (WB)

other info1 :

Organism Species: Homo sapiens (Human). Source: Monoclonal antibody preparation. Traits: Liquid. Immunogen: Recombinant TNFSF14 (His62~Val240) expressed in E.coli

other info2 :

Conjugated Antibody: The APC conjugated antibody version of this item is also available as catalog #MBS2048225

ncbi gi num :

25952144

ncbi acc num :

NP_003798.2

ncbi gb acc num :

NM_003807.4

uniprot acc num :

O43557

ncbi pathways :

Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Herpes Simplex Infection Pathway (377873); Herpes Simplex Infection Pathway (377865); NF-kappa B Signaling Pathway (634527)

ncbi summary :

The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14, which is a member of the tumor necrosis factor receptor superfamily, and which is also known as a herpesvirus entry mediator (HVEM). This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells. This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

uniprot summary :

TNFSF14: Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Activates NFKB, stimulates the proliferation of T-cells, and inhibits growth of the adenocarcinoma HT-29. Acts as a receptor for Herpes simplex virus. Belongs to the tumor necrosis factor family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Cytokine; Inhibitor; Membrane protein, integral. Chromosomal Location of Human Ortholog: 19p13.3. Cellular Component: cytoplasm; extracellular space; integral component of membrane; plasma membrane. Molecular Function: caspase inhibitor activity; cytokine activity; protein binding; receptor binding; tumor necrosis factor receptor binding. Biological Process: apoptosis; immune response; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; positive regulation of myoblast differentiation; release of cytoplasmic sequestered NF-kappaB; signal transduction; T cell activation; T cell costimulation; T cell homeostasis; T cell proliferation; tumor necrosis factor-mediated signaling pathway

size1 :

0.01 mg

price1 :

100 USD

size2 :

0.02 mg

price2 :

110

size3 :

0.05 mg

price3 :

140

size4 :

0.1 mg

price4 :

170

size5 :

0.2 mg

price5 :

220

size6 :

1 mg

price6 :

495

more info or order :

MyBioSource product webpage