protein

Recombinant Carbohydrate Antigen 125 (CA125)

MBS2012364

0.01 mg

145 USD

Recombinant Protein

Recombinant Carbohydrate Antigen 125 (CA125)

[Carbohydrate Antigen 125 (CA125)]

[mucin-16; Mucin-16; mucin-16; CA-125; MUC-16; CA125 ovarian cancer antigen; ovarian carcinoma antigen CA125; ovarian cancer-related tumor marker CA125; mucin 16, cell surface associated; Ovarian cancer-related tumor marker CA125; CA-125; Ovarian carcinoma antigen CA125]

[CA125]

[MUC16; MUC16; CA125; CA125; MUC-16; CA-125]

MUC16_HUMAN

E.coli

> 95%

100mM NaHCO 3 , 500mM NaCl, pH8.3, containing 0.01% sarcosyl, 5%Trehalose.

Original Concentration: 550ug/mL

Storage: Avoid repeated freeze/thaw cycles. Store at 2-8ºC for one month. Aliquot and store at -80ºC for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Positive Control; Immunogen; SDS-PAGE; Western Blot (WB).

Sequence

Identification

SDS-Page

Organism Species: Homo sapiens (Human). Source: Prokaryotic expression. Residues: Arg13977~Ser14117. Tags: N-terminal His Tag. Subcellular Location: Membrane, Secreted. Traits: Freeze-dried powder

Predicted isoelectric point: 6.2. Phenomenon explanation: The possible reasons that the actual band size differs from the predicted are as follows:. 1.Splice variants: Alternative splicing may create different sized proteins from the same gene. 2. Relative charge: The composition of amino acids may affects the charge of the protein. 3. Post-translational modification: Phosphorylation, glycosylation, methylation etc. 4. Post-translation cleavage: Many proteins are synthesized as pro-proteins, and then cleaved to give the active form. 5. Polymerization of the target protein: Dimerization, multimerization etc. Usage: Reconstitute in ddH2O to a concentration of 0.1-1.0 mg/mL. Do not vortex.

83367077

NP_078966.2

NM_024690.2

Q8WXI7

Predicted Molecular Mass: 22.2kDa. Accurate Molecular Mass: 26kDa as determined by SDS-PAGE reducing conditions.

Metabolism Of Proteins Pathway (106230); O-linked Glycosylation Of Mucins Pathway (530747); Post-translational Protein Modification Pathway (161012); Termination Of O-glycan Biosynthesis Pathway (530748)

MUC16: Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. Protein type: Membrane protein, peripheral; Cell adhesion; Membrane protein, integral. Chromosomal Location of Human Ortholog: 19p13.2. Cellular Component: extracellular space; extrinsic to membrane; Golgi lumen; integral to membrane; plasma membrane; vesicle. Molecular Function: protein binding. Biological Process: protein amino acid O-linked glycosylation; cellular protein metabolic process; O-glycan processing; cell adhesion; post-translational protein modification

0.01 mg

145 USD

0.05 mg

280

0.1 mg

435

0.2 mg

535

0.5 mg

1035

1 mg

1540