protein

Recombinant Microtubule Associated Protein 2 (MAP2)

MBS2012357

0.01 mg

185 USD

Recombinant Protein

Recombinant Microtubule Associated Protein 2 (MAP2)

Microtubule Associated Protein 2 (MAP2)

microtubule-associated protein 2 isoform 5; Microtubule-associated protein 2; microtubule-associated protein 2; MAP-2; microtubule-associated protein 2

MAP2

MAP2; MAP2; MAP2A; MAP2B; MAP2C; MAP-2

MTAP2_HUMAN

E Coli

559

The sequence of the target protein is listed below. LASD ILTNTSGSMD EGDDYLPATT PALEKAPCFP VESKEEEQIE KVKATGEEST QAEISCESPF LAKDFYKNGT VMAPDLPEML DLAGTRSRLA SVSADAEVAR RKSVPSETVV EDSRTGLPPV TDENHVIVKT DSQLEDLGYC VFNKYTVPLP SPVQDSENLS GESGTFYEGT DDKVRRDLAT DLSLIEVKLA AAGRVKDEFS VDKEASAHIS GDKSGLSKEF DQEKKANDRL DTVLEKSEEH ADSKEHAKKT EEAGD

> 95%

Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl.

Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months. Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.

SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)

Organism: Homo sapiens (Human). Expression System: Prokaryotic expression. Residues: Leu727~Asp985 (Accession # P11137) with N-terminal His-Tag. Subcellular Location: Cytoplasm, cytoskeleton. Predicted isoelectric point: 4.7. Predicted Molecular Mass: 29.7kDa. Accurate Molecular Mass: 43kDa as determined by SDS-PAGE reducing conditions.

Endotoxin Level: <1.0EU per 1ug (determined by the LAL method). Reconstitution: Reconstitute in sterile ddH2O.

87578394

NP_001034627.1

NM_001039538.1

P11137

LKB1 Signaling Events Pathway (137957); MAPK Cascade Pathway (198834); SIDS Susceptibility Pathways (198901)

This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jan 2010]

MAP2: a member of the microtubule-associated protein (MAP) family. Its exact function is unknown but MAPs appear to stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules. Expressed at high levels in neural tissue and the prostate. Four alternatively spliced transcript variants have been reported. Protein type: Motility/polarity/chemotaxis; Cytoskeletal. Chromosomal Location of Human Ortholog: 2q34-q35. Cellular Component: microtubule; microtubule associated complex; cell soma; cytoplasm; nucleolus; dendritic shaft. Molecular Function: calmodulin binding; protein binding; microtubule binding; structural molecule activity. Biological Process: axonogenesis; dendrite morphogenesis; microtubule bundle formation; neurite development; central nervous system neuron development

0.01 mg

185 USD

0.05 mg

380

0.1 mg

585