Recombinant Kallikrein 7 (KLK7) | MyBioSource MBS2012354 product information

product summary

company name :

MyBioSource

product type :

protein

product name :

Recombinant Kallikrein 7 (KLK7)

catalog :

MBS2012354

quantity :

0.01 mg

price :

210 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS2012354

products type :

Recombinant Protein

products full name :

Recombinant Kallikrein 7 (KLK7)

products short name :

Kallikrein 7 (KLK7)

other names :

glandular kallikrein-7, submandibular/renal; Glandular kallikrein-7, submandibular/renal; glandular kallikrein-7, submandibular/renal; esterase B; kallikrein 5; kallikrein 7; proteinase A; renal kallikrein; tissue kallikrein; kallikrein 1-like peptidase; kallikrein-related protein K1; Kallikrein 1 renal/pancreas/salivary; Kallikrein 1, renal/pancreas/salivary; kallikrein 1-related peptidase C7; Esterase B; Kallikrein-related protein K1; Proteinase A; RSKG-7; Tissue kallikrein

products gene name :

KLK7

other gene names :

Klk1c7; Klk7; Kal; KALA; Klk1; Klk5; Klk7; Klk1l; RGK-7; RSKG-7; RATKALA; Klk-7; rGK-7

uniprot entry name :

KLK7_RAT

host :

E Coli

sequence length :

261

sequence :

The target protein is fused with two N-terminal Tags, His-tag and GST-tag, its sequence is listed below. MRNKKFELGL EFPNLPYYID GDVKLTQSMA IIRYIADKHN MLGGCPKERA EISMLEGAVL DIRYGVSRIA YSKDFETLKV DFLSKLPEML KMFEDRLCHK TYLNGDHVTH PDFMLYDALD VVLYMDPMCL DAFPKLVCFK KRIEAIPQID KYLKSSKYIA WPLQGWQATF GGGDHPPKSD GSTSGSGHHH HHHSAGLVPR GSTAIGMKET AAAKFERQHM DSPDLGTLEV LFQGPLGS-RVIGGYK CEKNSQPWQV ALYSFTKYLC GGVLIDPSWV ITAAHCSSNN YQVWLGRNNL LEDEPFAQHR LVSQSFPHPD YKPFLMRNHT RKPGDDHSNDLMLLHLSQPA DITDGVKVID LPTEEPKVGS TCLASGWGST KPLIWEFPDD LQCVNIHLLS NEKCIKAYKE KVTDLMLCAG ELEGGKDTCT GDSGGPLLCD GVLQGITSWG SVPCAKTNMP AIYTKLIKFT SWIKE

purity :

> 95%

form :

Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.05% sarcosyl.

storage stability :

Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months. Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.

tested application :

SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP). (May be suitble for use in other assays to be dertermined by the end user.)

other info1 :

Organism: Rattus norvegicus (Rat). Expression System: Prokaryotic expression. Residues: Arg24~Glu255 (Accession # P36373) with two N-terminal Tags, His-tag and GST-tag

other info2 :

Endotoxin Level: <1.0EU per 1ug (determined by the LAL method). Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4. Predicted isoelectric point: 6.1

products description :

About the Marker: . Effective Size Range: 10kDa to 70kDa. Protein bands: 10kDa, 14kDa, 18kDa, 22kDa, 26kDa, 33kDa, 44kDa and70kDa. Double intensity bands: The 26kDa, 18kDa, 10kDa bands are at doubleintensity to make location and size approximation of proteins of interestquick and easy. Ready-to-use: No need to heat, dilute or add reducing agents before use.

ncbi gi num :

6981132

ncbi acc num :

NP_036725.1

ncbi gb acc num :

NM_012593.1

uniprot acc num :

P36373

ncbi mol weight :

57.5kDa

ncbi pathways :

Endocrine And Other Factor-regulated Calcium Reabsorption Pathway (213301); Endocrine And Other Factor-regulated Calcium Reabsorption Pathway (213276)

ncbi summary :

serine protease; involved in processing of bioactive peptides [RGD, Feb 2006]

uniprot summary :

KLK7: May catalyze the degradation of intercellular cohesive structures in the cornified layer of the skin in the continuous shedding of cells from the skin surface. Specific for amino acid residues with aromatic side chains in the P1 position. SCCE cleaves insulin B chain at 6-Leu- -Cys-7 , 16-Tyr- -Leu-17 , 25-Phe- -Tyr-26 and 26-Tyr- -Thr-27 . Could play a role in the activation of precursors to inflammatory cytokines. Belongs to the peptidase S1 family. Kallikrein subfamily. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Protease; Secreted, signal peptide; Secreted; EC 3.4.21.35. Cellular Component: apical part of cell; acrosome; nucleus. Molecular Function: serine-type endopeptidase activity; endopeptidase activity. Biological Process: positive regulation of acute inflammatory response; positive regulation of apoptosis; positive regulation of cell proliferation; proteolysis; response to nutrient

size1 :

0.01 mg

price1 :

210 USD

size2 :

0.05 mg

price2 :

465

size3 :

0.1 mg

price3 :

720

more info or order :

MyBioSource product webpage