protein

Recombinant Thy1 Cell Surface Antigen (Thy1)

MBS2012347

0.01 mg

170 USD

Recombinant Protein

Recombinant Thy1 Cell Surface Antigen (Thy1)

Thy1 Cell Surface Antigen (Thy1)

thy-1 membrane glycoprotein preproprotein; Thy-1 membrane glycoprotein; thy-1 membrane glycoprotein; CDw90; thy-1 antigen; Thy-1 T-cell antigen; Thy-1 cell surface antigen; CDw90; Thy-1 antigen

Thy1

THY1; THY1; CD90

THY1_HUMAN

E Coli

161

The target protein is fused with N-terminal His-Tag, its sequence is listed below. MGHHHHHHSGSEF-QKVTSLTACL VDQSLRLDCR HENTSSSPIQ YEFSLTRETK KHVLFGTVGV PEHTYRSRTN FTSKYNMKVL YLSAFTSKDE GTYTCALHHS GHSPPISSQN VTVLRDKLVK CEGI

> 95%

Supplied as lyophilized form in 10mM PBS, pH7.4, containing 1mM DTT, 5% trehalose, 0.01% sarcosyl and preservative.

Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months. Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.

SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)

Organism: Homo sapiens (Human). Expression System: Prokaryotic expression. Residues: Gln20~Ile133 (Accession # P04216) with N-terminal His-Tag. Subcellular Location: Cell membrane; Lipid-anchor, GPI-anchor.

Endotoxin Level: <1.0EU per 1ug (determined by the LAL method). Predicted isoelectric point: 8.7. Predicted Molecular Mass: 14.4kDa. Reconstitution: Reconstitute in sterile ddH2O.

19923362

NP_006279.2

NM_006288.3

P04216

Cardiac Progenitor Differentiation Pathway (712094); IL4-mediated Signaling Events Pathway (137933); Leukocyte Transendothelial Migration Pathway (83083); Leukocyte Transendothelial Migration Pathway (494); Amb2 Integrin Signaling Pathway (137945)

This gene encodes a cell surface glycoprotein and member of the immunoglobulin superfamily of proteins. The encoded protein is involved in cell adhesion and cell communication in numerous cell types, but particularly in cells of the immune and nervous systems. The encoded protein is widely used as a marker for hematopoietic stem cells. This gene may function as a tumor suppressor in nasopharyngeal carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]

THY1: May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain. Protein type: Cell adhesion; Motility/polarity/chemotaxis; Membrane protein, GPI anchor. Chromosomal Location of Human Ortholog: 11q23.3. Cellular Component: anchored to external side of plasma membrane; focal adhesion; growth cone; integral to plasma membrane; endoplasmic reticulum; apical plasma membrane; dendrite; plasma membrane; cytosol; external side of plasma membrane; lipid raft. Molecular Function: integrin binding; protein binding; protein kinase binding. Biological Process: focal adhesion formation; cell-cell adhesion; retinal cone cell development; negative regulation of T cell receptor signaling pathway; negative regulation of protein kinase activity; negative regulation of axonogenesis; cytoskeleton organization and biogenesis; angiogenesis; positive regulation of release of sequestered calcium ion into cytosol; positive regulation of T cell activation; negative regulation of cell migration; T cell receptor signaling pathway; positive regulation of GTPase activity

0.01 mg

170 USD

0.05 mg

345

0.1 mg

535