catalog number :
MBS2012140
products type :
Recombinant Protein
products full name :
Recombinant Metallothionein 1 (MT1)
products short name :
[Metallothionein 1 (MT1)]
other names :
[metallothionein-1A; Metallothionein-1A; metallothionein-1A; MT-1A; MT-IA; metallothionein 1S; metallothionein-IA; metallothionein 1A (functional); metallothionein 1A; Metallothionein-IA]
products gene name :
[MT1]
other gene names :
[MT1A; MT1A; MT1; MTC; MT1S; MT1S; MT-1A; MT-IA]
uniprot entry name :
MT1A_HUMAN
form :
20mM Tris, 150mM NaCl, pH8.0, containing 0.01% SKL, 5% Trehalose.
concentration :
Original Concentration: 200ug/mL
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store at 2-8ºC for one month. Aliquot and store at -80ºC for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
tested application :
Positive Control; Immunogen; SDS-PAGE; Western Blot (WB)
app notes :
(May be suitable for use in other assays to be determined by the end user.)
image1 heading :
Sequence
image2 heading :
SDS-PAGE
image3 heading :
Gene Sequencing (Extract)
other info1 :
Organism Species: Homo sapiens (Human). Source: Prokaryotic expression. Residues: Met1~Gly52. Tags: N-terminal His Tag. Subcellular Location: n/a. Traits: Freeze-dried powder. Predicted isoelectric point: 8.7
other info2 :
Phenomenon explanation: The possible reasons that the actual band size differs from the predicted are as follows: . 1. Splice variants: Alternative splicing may create different sized proteins from the same gene. 2. Relative charge: The composition of amino acids may affects the charge of the protein. 3. Post-translational modification: Phosphorylation, glycosylation, methylation etc. 4. Post-translation cleavage: Many proteins are synthesized as pro-proteins, and then cleaved to give the active form. 5. Polymerization of the target protein: Dimerization, multimerization etc. Usage: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
ncbi acc num :
NP_005937.2
ncbi gb acc num :
NM_005946.2
uniprot summary :
MT1: Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids. Belongs to the metallothionein superfamily. Type 1 family. Chromosomal Location of Human Ortholog: 16q13. Cellular Component: perinuclear region of cytoplasm; cytoplasm; nucleus. Molecular Function: protein binding; zinc ion binding. Biological Process: negative regulation of growth