product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Histone Cluster 2, H2ac (HIST2H2AC)
catalog :
MBS2012098
quantity :
0.01 mg
price :
140 USD
more info or order :
image
image 1 :
image 2 :
product information
catalog number :
MBS2012098
products type :
Recombinant Protein
products full name :
Recombinant Histone Cluster 2, H2ac (HIST2H2AC)
products short name :
[Histone Cluster 2, H2ac (HIST2H2AC)]
other names :
[histone H2A type 2-C; Histone H2A type 2-C; histone H2A type 2-C; histone IIa; histone H2A/q; histone 2, H2ac; histone H2A-GL101; H2A histone family, member Q; histone cluster 2, H2ac; Histone H2A-GL101; Histone H2A/q]
products gene name :
[HIST2H2AC]
other gene names :
[HIST2H2AC; HIST2H2AC; H2A; H2A/q; H2AFQ; H2A-GL101; H2AFQ]
uniprot entry name :
H2A2C_HUMAN
host :
E Coli
reactivity :
Human
purity :
> 95%
form :
20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5%Trehalose and Proclin300
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed.The loss rate is less than 5% within the expiration date under appropriate storage condition.
tested application :
SDS-PAGE, WB, ELISA, IP, CoIP, Purification, Amine Reactive Labeling. (May be suitable for use in other assays to be determined by the end user.)
image1 heading :
Sequence Information
image2 heading :
SDS-Page
other info1 :
Source: Prokaryotic expression. Residues: Met1~Lys129. Tags: Two N-terminal Tags, His-tag and GST-tag. Tissue Specificity: Lung. Subcellular Location: Nucleus. Chromosome. Traits: Freeze-dried powder
other info2 :
Predicted isoelectric point: 10.9. Predicted Molecular Mass: 44.0kDa. Accurate Molecular Mass: 44kDa as determined by SDS-PAGE reducing conditions. Usage: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex
ncbi gi num :
24638446
ncbi acc num :
NP_003508.1
ncbi gb acc num :
NM_003517.2
uniprot acc num :
Q16777
ncbi pathways :
Alcoholism Pathway (585563); Alcoholism Pathway (587116); Amyloids Pathway (366238); Cell Cycle Pathway (530733); Cell Cycle, Mitotic Pathway (105765); Cellular Senescence Pathway (905991); Cellular Responses To Stress Pathway (645258); Chromatin Modifying Enzymes Pathway (941403); Chromatin Organization Pathway (941402); Chromosome Maintenance Pathway (161048)
ncbi summary :
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. [provided by RefSeq, Aug 2015]
uniprot summary :
HIST2H2AC: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. Belongs to the histone H2A family. Protein type: DNA-binding. Chromosomal Location of Human Ortholog: 1q21.2. Cellular Component: nucleosome; nucleus. Molecular Function: DNA binding; protein heterodimerization activity
size1 :
0.01 mg
price1 :
140 USD
size2 :
0.05 mg
price2 :
260
size3 :
0.1 mg
price3 :
400
size4 :
0.2 mg
price4 :
495
size5 :
0.5 mg
price5 :
955
size6 :
1 mg
price6 :
1415
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
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