catalog number :
MBS2011994
products type :
Recombinant Protein
products full name :
Recombinant Anti-Mullerian Hormone (AMH)
products short name :
Anti-Mullerian Hormone (AMH)
other names :
muellerian-inhibiting factor; Muellerian-inhibiting factor; muellerian-inhibiting factor; anti-Muellerian hormone; muellerian-inhibiting substance; Anti - Mullerian hormone (Mulerian inhibiting substance); anti-Mullerian hormone; Anti-Muellerian hormone; AMH; Muellerian-inhibiting substance
other gene names :
Amh; Amh; MIS; AMH; MIS
uniprot entry name :
MIS_RAT
reactivity :
Rattus norvegicus (Rat)
sequence :
The target protein is fused with N-terminal His-Tag, its sequence is listed below. MGHHHHHHSGS-KGTG TDGLCALREL SVDLRAERSV LIPETYQANN CQGACAWPQS DRNPRYGNHV VLLLKMQARG AALGRLPCCV PTAYTGKLLI SLSEEHISAH HVPNMVATEC GCR
form :
Supplied as lyophilized form in PBS, pH7.4, containing 1mM DTT, 5% trehalose, 0.01% sarcosyl and preservative.
storage stability :
Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months. Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
tested application :
SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
other info1 :
Predicted isoelectric point: 8.2. Expression System: Prokaryotic expression. Residues: Lys447~Arg553 (Accession # P49000) with N-terminal His-Tag
other info2 :
Endotoxin Level: <1.0EU per 1ug (determined by the LAL method). Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.
products description :
About the Marker: Effective Size Range: 10kDa to 70kDa. Protein bands: 10kDa, 14kDa, 18kDa, 22kDa, 26kDa, 33kDa, 44kDa and70kDa. Double intensity bands: The 26kDa, 18kDa, 10kDa bands are at doubleintensity to make location and size approximation of proteins of interestquick and easy. Ready-to-use: No need to heat, dilute or add reducing agents before use.
ncbi acc num :
NP_037034.1
ncbi gb acc num :
NM_012902.1
ncbi mol weight :
12.8kDa
ncbi pathways :
Cytokine-cytokine Receptor Interaction Pathway (83443); Cytokine-cytokine Receptor Interaction Pathway (460); Hippo Signaling Pathway (749790); Hippo Signaling Pathway (750388); TGF-beta Signaling Pathway (83456); TGF-beta Signaling Pathway (475)
ncbi summary :
ligand for MIS receptor II that suppresses female primary and secondary sexual development and allows male sexual differentiation to occur [RGD, Feb 2006]
uniprot summary :
Function: This glycoprotein, produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin. Subunit structure: Homodimer; disulfide-linked. Subcellular location: Secreted . By similarity. Sequence similarities: Belongs to the TGF-beta family.