protein

Recombinant Integrin Associated Protein (IAP)

MBS2011878

0.01 mg

130 USD

Recombinant Protein

Recombinant Integrin Associated Protein (IAP)

[Integrin Associated Protein (IAP)]

[leukocyte surface antigen CD47; Leukocyte surface antigen CD47; leukocyte surface antigen CD47; Rh-related antigen; integrin-associated protein; CD47 antigen (Rh-related antigen, integrin-associated signal transducer); Integrin-associated protein]

[IAP]

[Cd47; Cd47; IAP; Itgp; AA407862; AI848868; AW108519; 9130415E20Rik; B430305P08Rik; IAP]

CD47_MOUSE

E Coli

> 90%

Original Concentration: 200 Ug/mL

Storage: Avoid repeated freeze/thaw cycles. Store at 2-8ºC for one month. Aliquot and store at -80ºC for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Positive Control, Immunogen, SDS-PAGE, WB. (May be suitable for use in other assays to be determined by the end user.)

Sequence Information

SDS-Page

Organism Species: Mus musculus (Mouse). Source: Prokaryotic expression. Residues: Ala18~Gly219. Tags: N-terminal His Tag. Subcellular Location: Membrane. Traits: Freeze-dried powder. Buffer formulation: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.

Predicted isoelectric point: 7.7. Predicted Molecular Mass: 23.7kDa. Accurate Molecular Mass: 23kDa as determined by SDS-PAGE reducing conditions. [ USAGE ]: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

6754382

NP_034711.1

NM_010581.3

Q61735

Cell Surface Interactions At The Vascular Wall Pathway (925994); Cell-Cell Communication Pathway (926576); ECM-receptor Interaction Pathway (83265); ECM-receptor Interaction Pathway (479); Extracellular Matrix Organization Pathway (927061); Hemostasis Pathway (925961); Integrin Cell Surface Interactions Pathway (927077); Signal Regulatory Protein (SIRP) Family Interactions Pathway (926586); Spinal Cord Injury Pathway (739004); XPodNet - Protein-protein Interactions In The Podocyte Expanded By STRING Pathway (755427)

CD47: Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus. Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection. 4 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, multi-pass; Membrane protein, integral; Motility/polarity/chemotaxis. Cellular Component: membrane; integral to plasma membrane; plasma membrane; integral to membrane. Molecular Function: protein binding. Biological Process: cell migration; response to bacterium; positive regulation of phagocytosis; positive regulation of cell proliferation; positive regulation of cell-cell adhesion; opsonization; positive regulation of T cell activation; signal transduction; cell adhesion; positive regulation of inflammatory response

0.01 mg

130 USD

0.05 mg

225

0.1 mg

340

0.2 mg

415

0.5 mg

800

1 mg

1180