protein

Recombinant Neuropilin 2 (NRP2)

MBS2011819

0.01 mg

150 USD

Recombinant Protein

Recombinant Neuropilin 2 (NRP2)

[Neuropilin 2 (NRP2)]

[neuropilin-2; Neuropilin-2; neuropilin-2; vascular endothelial cell growth factor 165 receptor 2; neuropilin 2; Vascular endothelial cell growth factor 165 receptor 2]

[NRP2]

[Nrp2; Nrp2]

NRP2_RAT

E. coli

Rat

>98%

20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5%Trehalose and Proclin300

200ug/mL

Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Positive Control, Immunogen, SDS-PAGE, WB. (May be suitable for use in other assays to be determined by the end user.)

Sequence Information

SDS-Page

Source: Prokaryotic expression. Residues: Glu652~Pro858. Tags: Two N-terminal Tags, His-tag and GST-tag. Tissue Specificity: Brain, Liver. Subcellular Location: Membrane; Single-pass type I membrane protein. Traits: Freeze-dried powder

Predicted isoelectric point: 5.3. Predicted Molecular Mass: 53.3kDa. Accurate Molecular Mass: 58kDa as determined by SDS-PAGE reducing conditions. Phenomenon explanation: The possible reasons that the actual band size differs from the predicted are as follows:. 1. Splice variants: Alternative splicing may create different sized proteins from the same gene. 2. Relative charge: The composition of amino acids may affects the charge of the protein. 3. Post-translational modification: Phosphorylation, glycosylation, methylation etc. 4. Post-translation cleavage: Many proteins are synthesized as pro-proteins, and then cleaved to give the active form. 5. Polymerization of the target protein: Dimerization, multimerization etc. Usage: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

13540699

NP_110496.1

NM_030869.3

O35276

Axon Guidance Pathway (936266); Developmental Biology Pathway (936265); L1CAM Interactions Pathway (936286); Neurophilin Interactions With VEGF And VEGFR Pathway (936069); NrCAM Interactions Pathway (936291); Signal Transduction Pathway (935956); Signaling By VEGF Pathway (936066); VEGF Ligand-receptor Interactions Pathway (936067)

an axonal guidance molecule [RGD, Feb 2006]

Function: High affinity receptor for semaphorins 3C, 3F, VEGF-165 and VEGF-145 isoforms of VEGF, and the PLGF-2 isoform ofPGF. Subunit structure: Heterodimer with NRP1. Binds PLXNB1 . By similarity. Subcellular location: Membrane; Single-pass type I membrane protein. Tissue specificity: Found in certain neuronal populations of the CNS and in other non-neuronal tissues including mesenchymal tissue lining in the ribs. Domain: The tandem CUB domains mediate binding to semaphorin, while the tandem F5/8 domains are responsible for heparin and VEGF binding . By similarity. Sequence similarities: Belongs to the neuropilin family.Contains 2 CUB domains.Contains 2 F5/8 type C domains.Contains 1 MAM domain.

0.01 mg

150 USD

0.05 mg

285

0.1 mg

445

0.2 mg

550

0.5 mg

1060

1 mg

1580