protein

Recombinant Somatostatin (SST)

MBS2011722

0.01 mg

100 USD

Recombinant Protein

Recombinant Somatostatin (SST)

[Somatostatin (SST)]

[somatostatin preproprotein; Somatostatin; somatostatin; somatostatin-14; somatostatin-28; prepro-somatostatin; growth hormone release-inhibiting factor; somatostatin; Growth hormone release-inhibiting factor]

[SST]

[SST; SST; SMST]

SMS_HUMAN

E.coli

> 95%

20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.

Original Concentration: 200 ug/mL

Storage: Avoid repeated freeze/thaw cycles. Store at 2-8ºC for one month. Aliquot and store at -80ºC for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Positive Control, Immunogen, SDS-PAGE, WB. (May be suitable for use in other assays to be determined by the end user.)

Sequence Information

SDS-Page

Organism Species: Homo sapiens (Human). Source: Prokaryotic expression. Residues: Met1~Cys116. Tags: N-terminal His Tag . Subcellular Location: Secreted. Traits: Freeze-dried powder. Buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 0.01% SKL, 5% Trehalose.

Predicted isoelectric point: 5.6. Predicted Molecular Mass: 19.4kDa. Accurate Molecular Mass: 18kDa as determined by SDS-PAGE reducing conditions. Usage: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex

4507243

NP_001039.1

NM_001048.3

P61278

Class A/1 (Rhodopsin-like Receptors) Pathway (106357); G Alpha (i) Signalling Events Pathway (119550); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); Gastric Acid Secretion Pathway (154409); Gastric Acid Secretion Pathway (154383); Peptide Ligand-binding Receptors Pathway (106358); SIDS Susceptibility Pathways (198901); Signal Transduction Pathway (477114); Signaling By GPCR Pathway (106356)

The hormone somatostatin has active 14 aa and 28 aa forms that are produced by alternate cleavage of the single preproprotein encoded by this gene. Somatostatin is expressed throughout the body and inhibits the release of numerous secondary hormones by binding to high-affinity G-protein-coupled somatostatin receptors. This hormone is an important regulator of the endocrine system through its interactions with pituitary growth hormone, thyroid stimulating hormone, and most hormones of the gastrointestinal tract. Somatostatin also affects rates of neurotransmission in the central nervous system and proliferation of both normal and tumorigenic cells. [provided by RefSeq, Jul 2008]

SST: Somatostatin inhibits the release of somatotropin. Belongs to the somatostatin family. Protein type: Secreted, signal peptide; Secreted; Hormone. Chromosomal Location of Human Ortholog: 3q28. Cellular Component: extracellular space; cell soma; extracellular region. Molecular Function: hormone activity. Biological Process: response to drug; synaptic transmission; G-protein coupled receptor protein signaling pathway; negative regulation of cell proliferation; hyperosmotic response; cell surface receptor linked signal transduction; cell-cell signaling; response to steroid hormone stimulus; response to heat; induction of apoptosis by hormones; digestion; response to amino acid stimulus; regulation of cell migration; response to nutrient

0.01 mg

100 USD

0.05 mg

155

0.1 mg

210

0.2 mg

250

0.5 mg

470

1 mg

690