catalog number :
MBS2011606
products type :
Recombinant Protein
products full name :
Recombinant Fibulin 2 (FBLN2)
products short name :
[Fibulin 2 (FBLN2)]
other names :
[fibulin-2 isoform a; Fibulin-2; fibulin-2; FIBL-2; fibulin 2]
products gene name :
[FBLN2]
other gene names :
[FBLN2; FBLN2; FIBL-2]
uniprot entry name :
FBLN2_HUMAN
concentration :
Original Concentration: 200 ug/mL
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store at 2-8ºC for one month. Aliquot and store at -80ºC for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
tested application :
Positive Control; Immunogen; SDS-PAGE; WB. (May be suitable for use in other assays to be determined by the end user.)
image1 heading :
SDS-Page
other info1 :
Organism Specie: Homo sapiens (Human). Source: Prokaryotic expression. Residues: Ile858~Ser1069. Tags: N-terminal His Tag
. Subcellular Location: Secreted, Extracellular matrix. Traits: Freeze-dried powder
. Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
other info2 :
Predicted isoelectric point: 5.6. Predicted Molecular Mass: 24.3kDa. Accurate Molecular Mass: 27kDa as determined by SDS-PAGE reducing conditions. Usage: Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
ncbi acc num :
NP_001004019.1
ncbi gb acc num :
NM_001004019.1
ncbi pathways :
Elastic Fibre Formation Pathway (730310); Extracellular Matrix Organization Pathway (576262); Molecules Associated With Elastic Fibres Pathway (730311)
ncbi summary :
This gene encodes an extracellular matrix protein, which belongs to the fibulin family. This protein binds various extracellular ligands and calcium. It may play a role during organ development, in particular, during the differentiation of heart, skeletal and neuronal structures. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
uniprot summary :
FBLN2: Its binding to fibronectin and some other ligands is calcium dependent. Belongs to the fibulin family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 3p25.1. Cellular Component: extracellular matrix; proteinaceous extracellular matrix; extracellular region; vesicle. Molecular Function: extracellular matrix binding; extracellular matrix structural constituent; calcium ion binding. Biological Process: extracellular matrix organization and biogenesis