product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Podocin (PDCN)
catalog :
MBS2011495
quantity :
0.01 mg
price :
200 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS2011495
products type :
Recombinant Protein
products full name :
Recombinant Podocin (PDCN)
products short name :
Podocin (PDCN)
other names :
podocin; Podocin; podocin; nephrosis 2 homolog, podocin; nephrosis 2 idiopathic steroid-resistant (podocin); nephrosis 2, idiopathic, steroid-resistant (podocin); nephrosis 2, idiopathic, steroid-resistant
products gene name :
PDCN
other gene names :
Nphs2; Nphs2; podocin
uniprot entry name :
PODO_RAT
host :
E Coli
sequence length :
383
sequence :
The sequence of the target protein is listed below. RARSSSR KTHGRGSRSS SRDDKKSKAG RGNRGRARPD AGAERQSAGR TGTREEHRAP AATVVNVDEV RSPGEEGTEV VALLESERPE EGIKPSGLGA
purity :
> 95%
form :
Supplied as lyophilized form in PBS, pH7.4, containing 1mM DTT, 5% trehalose, 0.1% sarcosyl and preservative.
storage stability :
Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months. Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
tested application :
SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
other info1 :
Organism: Rattus norvegicus (Rat). Expression System: Prokaryotic expression. Residues: Arg4~Ala100 (Accession # Q8K4G9) with N-terminal His-Tag
other info2 :
Endotoxin Level: <1.0EU per 1ug (determined by the LAL method). Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4. Predicted isoelectric point: 10.4. Accurate Molecular Mass: 18kDa as determined by SDS-PAGE reducing conditions.
products description :
About the Marker: Effective Size Range: 10kDa to 70kDa. Protein bands: 10kDa, 14kDa, 18kDa, 22kDa, 26kDa, 33kDa, 44kDa and70kDa. Double intensity bands: The 26kDa, 18kDa, 10kDa bands are at doubleintensity to make location and size approximation of proteins of interestquick and easy. Ready-to-use: No need to heat, dilute or add reducing agents before use.
ncbi gi num :
31543335
ncbi acc num :
NP_570841.2
ncbi gb acc num :
NM_130828.2
uniprot acc num :
Q8K4G9
ncbi mol weight :
11.8kDa
ncbi summary :
may play a role in renal glomerular capillary wall function [RGD, Feb 2006]
uniprot summary :
NPHS2: Plays a role in the regulation of glomerular permeability, acting probably as a linker between the plasma membrane and the cytoskeleton. Defects in NPHS2 are the cause of nephrotic syndrome type 2 (NPHS2). It is a renal disorder characterized clinically by childhood onset of proteinuria, hypoalbuminemia, hyperlipidemia, and edema. Kidney biopsies show non-specific histologic changes such as focal segmental glomerulosclerosis and diffuse mesangial proliferation. The disorder is resistant to steroid treatment and progresses to end-stage renal failure in the first or second decades. Some patients show later onset of the disorder. Belongs to the band 7/mec-2 family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral. Cellular Component: protein complex; integral to plasma membrane; plasma membrane; intercellular junction; lipid raft. Biological Process: actin cytoskeleton reorganization; excretion
size1 :
0.01 mg
price1 :
200 USD
size2 :
0.05 mg
price2 :
430
size3 :
0.1 mg
price3 :
665
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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