Recombinant Bone Morphogenetic Protein 2 (BMP2) | MyBioSource MBS2011481 product information

product summary

company name :

MyBioSource

product type :

protein

product name :

Recombinant Bone Morphogenetic Protein 2 (BMP2)

catalog :

MBS2011481

quantity :

0.01 mg

price :

140 USD

more info or order :

MyBioSource product webpage

image

image 1 :

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product information

catalog number :

MBS2011481

products type :

Recombinant Protein

products full name :

Recombinant Bone Morphogenetic Protein 2 (BMP2)

products short name :

[Bone Morphogenetic Protein 2 (BMP2)]

other names :

[bone morphogenetic protein 2; Bone morphogenetic protein 2; bone morphogenetic protein 2; BMP-2; BMP-2A; bone morphogenetic protein 2A; bone morphogenetic protein 2; Bone morphogenetic protein 2A]

products gene name :

[BMP2]

other gene names :

[Bmp2; Bmp2; Bmp-2; BMP-2; BMP-2A]

uniprot entry name :

BMP2_RAT

host :

E Coli

purity :

> 90%

form :

PBS, pH7.4, containing 0.01% SKL, 5% Trehalose

concentration :

Original Concentration: 200 ug/mL

storage stability :

Storage: Avoid repeated freeze/thaw cycles. Store at 2-8ºC for one month. Aliquot and store at -80ºC for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

tested application :

Positive Control; Immunogen; SDS-PAGE; WB. (May be suitable for use in other assays to be determined by the end user.)

image1 heading :

Sequence Information

image2 heading :

SDS-Page

image3 heading :

Testing Data

other info1 :

Organism Species: Rattus norvegicus (Rat). Source: Prokaryotic expression. Residues: Ser49~Ile243. Tags: N-terminal His Tag. Subcellular Location: Secreted. Traits: Freeze-dried powder.

other info2 :

Predicted isoelectric point: 7.0. Predicted Molecular Mass: 23.6kDa. Accurate Molecular Mass: 26kDa as determined by SDS-PAGE reducing conditions. Usage: Reconstitute in PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex

ncbi gi num :

8392990

ncbi acc num :

NP_058874.1

ncbi gb acc num :

NM_017178.1

uniprot acc num :

P49001

ncbi pathways :

Adipogenesis Pathway (198479); Basal Cell Carcinoma Pathway (83501); Basal Cell Carcinoma Pathway (525); Elastic Fibre Formation Pathway (935784); Extracellular Matrix Organization Pathway (935777); Hedgehog Signaling Pathway (83455); Hedgehog Signaling Pathway (474); Hippo Signaling Pathway (749790); Hippo Signaling Pathway (750388); Id Signaling Pathway (198536)

ncbi summary :

involved in cellular signaling during limb development; induces bone formation [RGD, Feb 2006]

uniprot summary :

BMP2: Induces cartilage and bone formation. Belongs to the TGF-beta family. Protein type: Secreted; Motility/polarity/chemotaxis; Secreted, signal peptide. Cellular Component: extracellular space; protein complex; cell surface; cytoplasm; extracellular region. Molecular Function: protein domain specific binding; protein homodimerization activity; growth factor activity; protein heterodimerization activity; phosphatase activator activity; cytokine activity; SMAD binding; transforming growth factor beta receptor binding; retinol dehydrogenase activity; receptor binding. Biological Process: positive regulation of apoptosis; activation of MAPK activity; positive regulation of transcription, DNA-dependent; heart development; adrenocorticotropin hormone secreting cell differentiation; telencephalon regionalization; protein amino acid phosphorylation; cardiac muscle cell differentiation; regulation of apoptosis; BMP signaling pathway; ovulation cycle; chondrocyte differentiation; inner ear development; positive regulation of astrocyte differentiation; regulation of odontogenesis of dentine-containing teeth; pericardium development; positive regulation of neurogenesis; cell fate commitment; organ morphogenesis; mesenchymal cell differentiation; response to mechanical stimulus; regulation of MAPKKK cascade; positive regulation of osteoblast proliferation; positive regulation of fat cell differentiation; positive regulation of endothelial cell proliferation; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; positive regulation of cell differentiation; negative regulation of calcium-independent cell-cell adhesion; positive regulation of odontogenesis; proteoglycan metabolic process; embryonic heart tube anterior/posterior pattern formation; negative regulation of insulin-like growth factor receptor signaling pathway; thyroid stimulating hormone secreting cell differentiation; negative regulation of transcription from RNA polymerase II promoter; bone mineralization; negative regulation of cell cycle; negative regulation of cell proliferation; positive regulation of MAPKKK cascade; regulation of transcription, DNA-dependent; cardiac muscle morphogensis; negative regulation of aldosterone biosynthetic process; inflammatory response; positive regulation of Wnt receptor signaling pathway; cardiac cell differentiation; ossification; Notch signaling pathway; response to retinoic acid; protein destabilization; in utero embryonic development; positive regulation of bone mineralization; positive regulation of ossification; odontogenesis of dentine-containing teeth; osteoblast differentiation; positive regulation of osteoblast differentiation; telencephalon development; ureteric bud branching; cartilage development; response to hypoxia; epithelial to mesenchymal transition; positive regulation of protein amino acid phosphorylation; positive regulation of neuron differentiation; positive regulation of cell migration; growth

size1 :

0.01 mg

price1 :

140 USD

size2 :

0.05 mg

price2 :

260

size3 :

0.1 mg

price3 :

400

size4 :

0.2 mg

price4 :

495

size5 :

0.5 mg

price5 :

955

size6 :

1 mg

price6 :

1415

more info or order :

MyBioSource product webpage