product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Membrane Cofactor Protein (MCP)
catalog :
MBS2011476
quantity :
0.01 mg
price :
195 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS2011476
products type :
Recombinant Protein
products full name :
Recombinant Membrane Cofactor Protein (MCP)
products short name :
Membrane Cofactor Protein (MCP)
other names :
membrane cofactor protein; Membrane cofactor protein; membrane cofactor protein; CD46 antigen, complement regulatory protein; CD46 molecule, complement regulatory protein
products gene name :
MCP
other gene names :
Cd46; Cd46; Mcp; Mcp
uniprot entry name :
MCP_RAT
host :
E Coli
sequence length :
355
sequence :
The sequence of the target protein is listed below. MNGYY MVGMSVLQCE LNGNGDAFWN GHPPSCKKVY CLPPPKIKNG THTFTDIKVF KYHEAVIYSC DPNPGPDKFS LVGPSMLFCA GHNTWSSDPP ECKVVKCPFP VLQNGRQISR TEKKFSYQAL VLFQCLEGFY MEGSSMVVCG AKSSWEPSIP QCLKGPKPHS TKPPVYSESG YPSPREGIFG QEFDAWIIAL IVVTSVVGVI V
purity :
> 90%
form :
Supplied as lyophilized form in 20mM Tris, 500mM NaCI, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative.
storage stability :
Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months. Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
tested application :
SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
other info1 :
Organism: Rattus norvegicus (Rat). Expression System: Prokaryotic expression. Residues: Met136~Val341 (Accession # Q9Z0M4) with two N-terminal Tags, His-tag and GST-tag. Subcellular Location: Cytoplasmic vesicle, secretory vesicle, acrosome inner membrane; Single-pass membrane protein.
other info2 :
Endotoxin Level: <1.0EU per 1ug (determined by the LAL method). Predicted Isoelectric Point: 6.7. Reconstitution: Reconstitute in sterile ddH2O.
ncbi gi num :
9506883
ncbi acc num :
NP_062063.1
ncbi gb acc num :
NM_019190.1
uniprot acc num :
Q9Z0M4
ncbi mol weight :
54.4kDa
ncbi pathways :
Complement And Coagulation Cascades Pathway (198461); Complement And Coagulation Cascades Pathway (83465); Complement And Coagulation Cascades Pathway (484); Complement Cascade Pathway (936714); Immune System Pathway (936650); Innate Immune System Pathway (936679); Measles Pathway (213300); Measles Pathway (213277); Regulation Of Complement Cascade Pathway (936721)
ncbi summary :
may be involved in fertilization or reproduction; human homolog acts as an inhibitor of plasma membrane complement [RGD, Feb 2006]
uniprot summary :
Function: May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Ref.2 Ref.3. Subcellular location: Cytoplasmic vesicle secretory vesicle acrosome inner membrane; Single-pass membrane protein. Note: Inner acrosomal membrane of spermatozoa. Ref.3. Tissue specificity: Specifically expressed in testis. Within testis, present only in elongated spermatids and spermatozoa (at protein level). Ref.1 Ref.2 Ref.3. Developmental stage: Not expressed in embryonic and immature rats. Expressed in parallel with synthesis of spermatids. Ref.3. Post-translational modification: O-glycosylated. Ref.3N-glycosylated. Ref.3. Sequence similarities: Contains 4 Sushi (CCP/SCR) domains.
size1 :
0.01 mg
price1 :
195 USD
size2 :
0.05 mg
price2 :
415
size3 :
0.1 mg
price3 :
640
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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