protein

Recombinant Lysyl Oxidase Like Protein 4 (LOXL4)

MBS2011455

0.01 mg

185 USD

Recombinant Protein

Recombinant Lysyl Oxidase Like Protein 4 (LOXL4)

Lysyl Oxidase Like Protein 4 (LOXL4)

lysyl oxidase homolog 4; Lysyl oxidase homolog 4; lysyl oxidase homolog 4; lysyl oxidase related C; lysyl oxidase-like protein 4; lysyl oxidase-like 4 pseudogene; lysyl oxidase-related protein C; lysyl oxidase-like 4; Lysyl oxidase-like protein 4; Lysyl oxidase-related protein C

LOXL4

LOXL4; LOXL4; LOXC; LOXC

LOXL4_HUMAN

E Coli

756

The target protein is fused with N-terminal His-Tag, its sequence is listed below. MGHHHHHHSGSEF-GC QHENDAAVRC NVPNMGFQNQ VRLAGGRIPE EGLLEVQVEV NGVPRWGSVC SENWGLTEAMVACRQLGLGF AIHAYKETWF WSGTPRAQEV VMSGVRCSGT ELALQQCQRH GPVHCSHGGG RFLAGVSCMD SAPDLVMNAQLVQETAYLED RP

>95%

Supplied as lyophilized form in PBS, pH7.4, containing 1mM DTT, 5% trehalose, 0.01% sarcosyl and preservative.

Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months. Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.

SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)

Organism: Homo sapiens (Human). Expression System: Prokaryotic expression. Residues: Gly399~Pro552 (Accession # Q96JB6), with N-terminal His-Tag. Subcellular Location: Cytoplasm, cytoskeleton, cell cortex. Predicted isoelectric point: 6.0

Endotoxin Level: <1.0EU per 1ug (determined by the LAL method). Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

About the Marker: Effective Size Range: 10kDa to 70kDa. Protein bands: 10kDa, 14kDa, 18kDa, 22kDa, 26kDa, 33kDa, 44kDa and70kDa. Double intensity bands: The 26kDa, 18kDa, 10kDa bands are at doubleintensity to make location and size approximation of proteins of interestquick and easy. Ready-to-use: No need to heat, dilute or add reducing agents before use.

67782349

NP_115587.6

NM_032211.6

Q96JB6

18.3kDa

Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway (730306); Collagen Formation Pathway (645288); Crosslinking Of Collagen Fibrils Pathway (730308); Elastic Fibre Formation Pathway (730310); Extracellular Matrix Organization Pathway (576262)

This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. [provided by RefSeq, Jul 2008]

LOXL4: May modulate the formation of a collagenous extracellular matrix. Belongs to the lysyl oxidase family. Protein type: Oxidoreductase; Secreted; Secreted, signal peptide; EC 1.4.3.-. Chromosomal Location of Human Ortholog: 10q24. Cellular Component: extracellular space; membrane; receptor complex. Molecular Function: protein binding; copper ion binding; protein-lysine 6-oxidase activity; scavenger receptor activity. Biological Process: receptor-mediated endocytosis

0.01 mg

185 USD

0.05 mg

380

0.1 mg

585