Recombinant Adipose Differentiation Related Protein (ADRP) | MyBioSource MBS2011445 product information

product summary

company name :

MyBioSource

product type :

protein

product name :

Recombinant Adipose Differentiation Related Protein (ADRP)

catalog :

MBS2011445

quantity :

0.01 mg

price :

200 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS2011445

products type :

Recombinant Protein

products full name :

Recombinant Adipose Differentiation Related Protein (ADRP)

products short name :

Adipose Differentiation Related Protein (ADRP)

other names :

perilipin-2; Perilipin-2; perilipin-2; adipophilin; adipose differentiation-related protein; perilipin 2; Adipophilin; Adipose differentiation-related protein

products gene name :

ADRP

other gene names :

PLIN2; PLIN2; ADFP; ADRP; ADFP; ADRP

uniprot entry name :

PLIN2_HUMAN

host :

E Coli

sequence length :

437

sequence :

The target protein is fused with N-terminal His-Tag, its sequence is listed below. MGHHHHHHSGSEF- KSQQTI SQLHSTVHLI EFARKNVYSA NQKIQDAQDK LYLSWVEWKR SIGYDDTDES HCAEHIESRT LAIARNLTQQ LQTTCHTLLS NIQGVPQNIQ DQAKHMGVMA GDIYSVFRNA ASFKEVSDSL LTSSKGQLQK MKESLDDVMD YLVNNTPLNW LVGPFYPQLT ESQNAQDQGA EMDKSSQETQ RSE

purity :

> 95%

form :

Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl.

storage stability :

Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months. Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.

tested application :

SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)

other info1 :

Organism: Homo sapiens (Human). Expression System: Prokaryotic expression. Residues: Lys245~Glu433 (Accession # Q99541) with N-terminal His-Tag. Subcellular Loacation: Membrane; Peripheral membrane protein. Predicted Isoelectric point: 5.8

other info2 :

Endotoxin Level: <1.0EU per 1ug (determined by the LAL method). Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

products description :

About the Marker: Effective Size Range: 10kDa to 70kDa. Protein bands: 10kDa, 14kDa, 18kDa, 22kDa, 26kDa, 33kDa, 44kDa and70kDa. Double intensity bands: The 26kDa, 18kDa, 10kDa bands are at doubleintensity to make location and size approximation of proteins of interestquick and easy. Ready-to-use: No need to heat, dilute or add reducing agents before use.

ncbi gi num :

34577059

ncbi acc num :

NP_001113.2

ncbi gb acc num :

NM_001122.3

uniprot acc num :

Q99541

ncbi mol weight :

23.0kDa

ncbi pathways :

Adipogenesis Pathway (198832); Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway (160977); HIF-1-alpha Transcription Factor Network Pathway (138045); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); PPARA Activates Gene Expression Pathway (530749); Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway (119544)

ncbi summary :

The protein encoded by this gene belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2011]

uniprot summary :

perilipin 2: May be involved in development and maintenance of adipose tissue. Belongs to the perilipin family. Protein type: Endoplasmic reticulum. Chromosomal Location of Human Ortholog: 9p22.1. Cellular Component: endoplasmic reticulum; extracellular region; plasma membrane; lipid particle; cytosol; nucleus. Biological Process: response to drug; long-chain fatty acid transport; sequestering of lipid; cellular lipid metabolic process; response to organic cyclic substance

size1 :

0.01 mg

price1 :

200 USD

size2 :

0.05 mg

price2 :

435

size3 :

0.1 mg

price3 :

670

more info or order :

MyBioSource product webpage