product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Pappalysin 2 (PAPPA2)
catalog :
MBS2011332
quantity :
0.01 mg
price :
145 USD
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS2011332 image 1
image 2 :
MyBioSource MBS2011332 image 2
product information
catalog number :
MBS2011332
products type :
Recombinant Protein
products full name :
Recombinant Pappalysin 2 (PAPPA2)
products short name :
[Pappalysin 2 (PAPPA2)]
other names :
[pappalysin-2 isoform 1; Pappalysin-2; pappalysin-2; placenta-specific 3; pregnancy-associated plasma protein E1; pregnancy-associated plasma preproprotein-A2; pappalysin 2; Pregnancy-associated plasma protein A2; PAPP-A2; Pregnancy-associated plasma protein E1]
products gene name :
[PAPPA2]
other gene names :
[PAPPA2; PAPPA2; PAPPE; PLAC3; PAPP-E; PAPP-A2; PLAC3; PAPP-A2; PAPP-E]
uniprot entry name :
PAPP2_HUMAN
host :
E Coli
reactivity :
Homo sapiens (Human)
purity :
>95%
form :
20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5%Trehalose and Proclin300.
concentration :
Original Concentration: 200ug/mL
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 24 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
tested application :
SDS-PAGE, WB, ELISA, IP, CoIP, Purification, Amine Reactive Labeling. (May be suitable for use in other assays to be determined by the end user.)
image1 heading :
Sequence Information
image2 heading :
SDS-Page
other info1 :
Source: Prokaryotic expression. Residues: Gly888~Ala1093. Tags: N-terminal His-Tag. Tissue Specificity: Breast, Kidney, Brain, Pancreas. Subcellular Location: Secreted
other info2 :
Traits: Freeze-dried powder. Predicted isoelectric point: 5.5. Predicted Molecular Mass: 24.4kDa. Accurate Molecular Mass: 27kDa as determined by SDS-PAGE reducing conditions. Usage: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
ncbi gi num :
116174738
ncbi acc num :
NP_064714.2
ncbi gb acc num :
NM_020318.2
uniprot acc num :
Q9BXP8
ncbi pathways :
Metabolism Of Proteins Pathway (106230); Regulation Of Insulin-like Growth Factor (IGF) Transport And Uptake By Insulin-like Growth Factor Binding Proteins (IGFBPs) Pathway (105908)
ncbi summary :
This gene encodes a member of the pappalysin family of metzincin metalloproteinases. The encoded protein cleaves insulin-like growth factor-binding protein 5 and is thought to be a local regulator of insulin-like growth factor (IGF) bioavailability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2010]
uniprot summary :
PAPPA2: Metalloproteinase which specifically cleaves IGFBP-5. Shows limited proteolysis toward IGFBP-3. Belongs to the peptidase M43B family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted, signal peptide; Protease; Secreted; EC 3.4.24.-. Chromosomal Location of Human Ortholog: 1q25.2. Cellular Component: membrane; extracellular region; intracellular. Molecular Function: metallopeptidase activity; zinc ion binding. Biological Process: cellular protein metabolic process; regulation of cell growth; proteolysis; cell differentiation
size1 :
0.01 mg
price1 :
145 USD
size2 :
0.05 mg
price2 :
275
size3 :
0.1 mg
price3 :
430
size4 :
0.2 mg
price4 :
525
size5 :
0.5 mg
price5 :
1015
size6 :
1 mg
price6 :
1515
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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