product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant A Disintegrin And Metalloproteinase With Thrombospondin 8 (ADAMTS8)
catalog :
MBS2011305
quantity :
0.01 mg
price :
185 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS2011305
products type :
Recombinant Protein
products full name :
Recombinant A Disintegrin And Metalloproteinase With Thrombospondin 8 (ADAMTS8)
products short name :
A Disintegrin And Metalloproteinase With Thrombospondin 8 (ADAMTS8)
other names :
A disintegrin and metalloproteinase with thrombospondin motifs 8 preproprotein; A disintegrin and metalloproteinase with thrombospondin motifs 8; A disintegrin and metalloproteinase with thrombospondin motifs 8; METH-2; METH-8; ADAMTS-8; ADAM-TS 8; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 8; ADAM metallopeptidase with thrombospondin type 1 motif, 8; METH-2; METH-8
products gene name :
ADAMTS8
other gene names :
ADAMTS8; ADAMTS8; METH2; ADAM-TS8; METH2; ADAM-TS 8; ADAM-TS8; ADAMTS-8
uniprot entry name :
ATS8_HUMAN
host :
E Coli
reactivity :
Human
purity :
> 95%
form :
PBS, pH7.4, containing 1mM DTT, 5% trehalose, 0.01% sarcosyl and Proclin300.
concentration :
200ug/mL
storage stability :
Storage : Avoid repeated freeze/thaw cycles.Store at 2-8 degree C for one month.Aliquot and store at -80 degree C for 12 months. Stability Test : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed.The loss rate is less than 5% within the expiration date under appropriate storage condition
tested application :
SDS-PAGE; WB; ELISA; IP; CoIP; Purification; Amine Reactive Labeling. (May be suitable for use in other assays to be determined by the end user.)
other info1 :
Source: Prokaryotic expression. Residues: Leu832~Leu889. Tags: N-terminal His-Tag. Tissue Specificity: Lung. Subcellular Location: Secreted, extracellular space, extracellular matrix. Traits: Freeze-dried powder
other info2 :
Predicted isoelectric point: 6.3. Predicted Molecular Mass: 7.6kDa. Accurate Molecular Mass: 13kDa as determined by SDS-PAGE reducing conditions. Usage: Reconstitute in PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex
ncbi gi num :
153792351
ncbi acc num :
NP_008968.4
ncbi gb acc num :
NM_007037.4
uniprot acc num :
Q9UP79
ncbi pathways :
Degradation Of The Extracellular Matrix Pathway (576263); Degradation Of The Extracellular Matrix Pathway (934113); Extracellular Matrix Organization Pathway (576262); Extracellular Matrix Organization Pathway (934100)
ncbi summary :
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs, and disrupts angiogenesis in vivo. A number of disorders have been mapped in the vicinity of this gene, most notably lung neoplasms. [provided by RefSeq, Jul 2008]
uniprot summary :
ADAMTS8: Has anti-angiogenic properties. Protein type: EC 3.4.24.-; Motility/polarity/chemotaxis; Secreted; Protease; Secreted, signal peptide; Cell cycle regulation. Chromosomal Location of Human Ortholog: 11q25. Cellular Component: extracellular matrix; proteinaceous extracellular matrix. Molecular Function: heparin binding; integrin binding; metallopeptidase activity; zinc ion binding; metalloendopeptidase activity; low affinity phosphate transmembrane transporter activity. Biological Process: negative regulation of cell proliferation; proteolysis
size1 :
0.01 mg
price1 :
185 USD
size2 :
0.05 mg
price2 :
380
size3 :
0.1 mg
price3 :
585
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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