Recombinant Bone Marrow Stromal Cell Antigen 1 (BST1) | MyBioSource MBS2010989 product information

product summary

company name :

MyBioSource

product type :

protein

product name :

Recombinant Bone Marrow Stromal Cell Antigen 1 (BST1)

catalog :

MBS2010989

quantity :

0.01 mg

price :

170 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS2010989

products type :

Recombinant Protein

products full name :

Recombinant Bone Marrow Stromal Cell Antigen 1 (BST1)

products short name :

Bone Marrow Stromal Cell Antigen 1 (BST1)

other names :

ADP-ribosyl cyclase 2; ADP-ribosyl cyclase 2; ADP-ribosyl cyclase 2; BST-1; cADPr hydrolase 2; NAD(+) nucleosidase; bone marrow stromal antigen 1; cyclic ADP-ribose hydrolase 2; bone marrow stromal cell antigen 1; Bone marrow stromal antigen 1; BST-1; Cyclic ADP-ribose hydrolase 2

products gene name :

BST1

other gene names :

BST1; BST1; CD157; BST-1

uniprot entry name :

BST1_HUMAN

host :

E Coli

sequence length :

318

sequence :

The target protein is fused with two N-terminal Tags, His-tag and T7-tag, its sequence is listed below. MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF-RNKNCTAI WEAFKVALDK DPCSVLPSDY DLFINLSRHS IPRDKSLFWE NSHLLVNSFA DNTRRFMPLS DVLYGRVADF LSWCRQKNDS GLDYQSCPTS EDCENNPVDS FWKRASIQYS KDSSGVIHVM LNGSEPTGAY PIKGFFADYE IPNLQKEKIT RIEIWVMHEI GGPNVESCGE GSMKVLEKRL KDMGFQYSCI NDYRPVKLLQ CVDHSTHPDC ALKSAAAATQ RKAPSLYTEQ RAGLIIPLFL VLA

purity :

> 95%

form :

Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl.

storage stability :

Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months. Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.

tested application :

SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)

other info1 :

Organism: Homo sapiens (Human). Expression System: Prokaryotic expression. Residues: Arg63~Ala313 (Accession # Q10588) with two N-terminal Tags, His-tag and T7-tag

other info2 :

Endotoxin Level: <1.0EU per 1ug (determined by the LAL method). Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

products description :

About the Marker: Effective Size Range: 10kDa to 70kDa. Protein bands: 10kDa, 14kDa, 18kDa, 22kDa, 26kDa, 33kDa, 44kDa and70kDa. Double intensity bands: The 26kDa, 18kDa, 10kDa bands are at doubleintensity to make location and size approximation of proteins of interestquick and easy. Ready-to-use: No need to heat, dilute or add reducing agents before use.

ncbi gi num :

168229159

ncbi acc num :

NP_004325.2

ncbi gb acc num :

NM_004334.2

uniprot acc num :

Q10588

ncbi mol weight :

32.3kDa

ncbi pathways :

Calcium Signaling Pathway (83050); Calcium Signaling Pathway (459); Epstein-Barr Virus Infection Pathway (585562); Epstein-Barr Virus Infection Pathway (587115); Nicotinate And Nicotinamide Metabolism Pathway (83014); Nicotinate And Nicotinamide Metabolism Pathway (400); Pancreatic Secretion Pathway (169306); Pancreatic Secretion Pathway (169295); Salivary Secretion Pathway (153376); Salivary Secretion Pathway (153352)

ncbi summary :

Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population. [provided by RefSeq, Jul 2008]

uniprot summary :

BST1: Synthesizes cyclic ADP-ribose, a second messenger that elicits calcium release from intracellular stores. May be involved in pre-B-cell growth. Belongs to the ADP-ribosyl cyclase family. Protein type: Cofactor and Vitamin Metabolism - nicotinate and nicotinamide; EC 3.2.2.6; Hydrolase; Membrane protein, GPI anchor. Chromosomal Location of Human Ortholog: 4p15. Cellular Component: extrinsic to membrane; plasma membrane. Molecular Function: transferase activity; phosphorus-oxygen lyase activity; NAD+ nucleosidase activity; NAD(P)+ nucleosidase activity. Biological Process: metabolic process; multicellular organismal development; positive regulation of B cell proliferation; humoral immune response

size1 :

0.01 mg

price1 :

170 USD

size2 :

0.05 mg

price2 :

345

size3 :

0.1 mg

price3 :

535

more info or order :

MyBioSource product webpage