catalog number :
MBS2010837
products type :
Recombinant Protein
products full name :
Recombinant Coiled Coil Domain Containing Protein 80 (CCDC80)
products short name :
[Coiled Coil Domain Containing Protein 80 (CCDC80)]
other names :
[coiled-coil domain-containing protein 80; Coiled-coil domain-containing protein 80; coiled-coil domain-containing protein 80; SSG-1; steroid sensitive gene 1; steroid sensitive gene-1 protein; steroid-sensitive gene 1 protein; down-regulated by oncogenes 1 protein; coiled-coil domain containing 80; Down-regulated by oncogenes 1 protein; Steroid-sensitive gene 1 protein]
products gene name :
[CCDC80]
other gene names :
[Ccdc80; Ccdc80; CL2; Dro1; Ssg1; Dro1; Ssg1; SSG-1]
uniprot entry name :
CCD80_RAT
concentration :
Original Concentration: 200 ug/mL
storage stability :
Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37°C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
tested application :
Immunogen, SDS-PAGE, Western Blot (WB), Positive Control (PC). (May be suitable for use in other assays to be determined by the end user.)
image1 heading :
SDS-Page
other info1 :
Organism: Rattus norvegicus (Rat). Source: Prokaryotic expression. Residues: Val82~Gly288. Traits: Freeze-dried powder. Buffer: 100mMNaHCO 3 , 500mMNaCl, pH8.3, containing 0.01% SKL, 5% Trehalose. Tags: N-terminal His Tag
other info2 :
Predicted isoelectric point: 9.7. Predicted Molecular Mass: 24.5kDa. Accurate Molecular Mass: 26kDa as determined by SDS-PAGE reducing conditions. Usage: Reconstitute in 100mM NaHCO 3 , 500mM NaCl (pH8.3) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
ncbi acc num :
NP_071988.2
ncbi gb acc num :
NM_022543.2
ncbi summary :
estrogen regulated gene; overexpression correlates with mammary carcinogenesis [RGD, Feb 2006]
uniprot summary :
Function: Promotes cell adhesion and matrix assembly . By similarity. Subunit structure: Binds to various extracellular matrix proteins . By similarity. Subcellular location: Secreted extracellular space extracellular matrix . By similarity. Note: Isoform 2:Cytoplasm. Ref.1. Tissue specificity: Isoform 2is expressed in uterus, liver, lung, spleen, kidney, heart, bladder, skeletal muscle and brain (at protein level). Isoform 2is expressed very low in mammary gland and intestine (at protein level). Isoform 2is expressed in lactating mammary glands and mammary tumors (at protein level). Ubiquitous (isoform 1) Isoform 2is expressed in ovary, uterus, mammary glands, liver, lung, spleen, kidney, heart, bladder, intestine, skeletal muscle and brain. Ref.1 Ref.2. Induction: Down-regulated by oncogenes (isoform 1) Isoform 2is down-regulated by beta estradiol in mammary gland (at mRNA level). Isoform 2is up-regulated by beta estradiol in mammary glands (at protein level). Up-regulated in lactating mammary glands and mammary tumors (at protein level). Ref.1 Ref.2. Post-translational modification: Phosphorylated . By similarity. Sequence similarities: Belongs to the CCDC80 family. Sequence caution: The sequence AAF35351.1 differs from that shown. Reason: Frameshift at several positions.