protein

Recombinant Peroxiredoxin 2 (PRDX2)

MBS2010800

0.01 mg

140 USD

Recombinant Protein

Recombinant Peroxiredoxin 2 (PRDX2)

[Peroxiredoxin 2 (PRDX2)]

[peroxiredoxin-2; Peroxiredoxin-2; peroxiredoxin-2; Prx II-1; Calpromotin; protector protein; thioredoxin reductase; thioredoxin peroxidase 1; Trx dependent peroxide reductase 1; thiol specific antioxidant protein; thiol-specific antioxidant protein; thioredoxin dependent peroxide reductase 1; thioredoxin-dependent peroxide reductase 1; peroxiredoxin 2; Thiol-specific antioxidant protein; TSA; Thioredoxin peroxidase 1; Thioredoxin-dependent peroxide reductase 1]

[PRDX2]

[Prdx2; Prdx2; TR; PRP; TPx; TSA; TDX1; NkefB; PrxII; TPx-B; Tdpx1; Torin; Band-8; AL022839; Tdpx1; Tpx; TSA]

PRDX2_MOUSE

E.coli

> 90%

Original Concentration: 200 ug/mL

Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Positive Control; Immunogen; SDS-PAGE; Western Blot (WB). (May be suitable for use in other assays to be determined by the end user.)

SDS-Page

Organism Species: Mus musculus (Mouse). Source: Prokaryotic expression. Residues: Ala6~Tyr164. Tags: N-terminal His-Tag. Subcellular Location: Cytoplasm. Endotoxin Level: 3 , 500mM NaCl, pH8.3, containing 0.01% sarcosyl, 5%Trehalose.

Predicted isoelectric point: 6.0. Predicted Molecular Mass: 18.8kDa. Accurate Molecular Mass: 18kDa as determined by SDS-PAGE reducing conditions. Usage: Reconstitute in ddH2O to a concentration of 0.1-1.0 mg/mL. Do not vortex.

148747558

NP_035693.3

NM_011563.5

Q61171

Cellular Responses To Stress Pathway (925999); Detoxification Of Reactive Oxygen Species Pathway (926005)

PRDX2: a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). May have a proliferative effect and play a role in cancer development or progression. Three splice-variant isoforms have been identified. Protein type: EC 1.11.1.15; Oxidoreductase. Cellular Component: mitochondrion; cytoplasm; cytosol; myelin sheath. Molecular Function: antioxidant activity; protein binding; selenium binding; peroxidase activity; thioredoxin peroxidase activity; peroxiredoxin activity; oxidoreductase activity. Biological Process: negative regulation of lipopolysaccharide-mediated signaling pathway; positive regulation of blood coagulation; removal of superoxide radicals; thymus development; activation of MAPK activity; respiratory burst during acute inflammatory response; homeostasis of number of cells; response to lipopolysaccharide; negative regulation of T cell differentiation; regulation of apoptosis; T cell proliferation; hydrogen peroxide catabolic process; inhibition of NF-kappaB transcription factor; hydrogen peroxide metabolic process; negative regulation of neuron apoptosis; response to oxidative stress; regulation of hydrogen peroxide metabolic process

0.01 mg

140 USD

0.05 mg

270

0.1 mg

420

0.2 mg

515

0.5 mg

990

1 mg

1475