catalog number :
MBS2010788
products type :
Recombinant Protein
products full name :
Recombinant A Disintegrin And Metalloproteinase With Thrombospondin 7 (ADAMTS7)
products short name :
A Disintegrin And Metalloproteinase With Thrombospondin 7 (ADAMTS7)
other names :
A disintegrin and metalloproteinase with thrombospondin motifs 7 preproprotein; A disintegrin and metalloproteinase with thrombospondin motifs 7; A disintegrin and metalloproteinase with thrombospondin motifs 7; COMPase; a disintegrin and metalloprotease with thrombospondin motifs-7 preproprotein; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 7; ADAM metallopeptidase with thrombospondin type 1 motif, 7; COMPase
products gene name :
ADAMTS7
other gene names :
ADAMTS7; ADAMTS7; ADAM-TS7; ADAMTS-7; ADAM-TS 7; ADAM-TS 7; ADAM-TS7; ADAMTS-7
uniprot entry name :
ATS7_HUMAN
sequence :
The target protein is fused with N-terminal His-Tag, its sequence is listed below. MGHHHHHHSGSEF-VQ RRLVKCVNTQ TGLPEEDSDQ CGHEAWPESS RPCGTEDCEP VEPPRCERDR LSFGFCETLR LLGRCQLPTI RTQCCRSCSP PSHGAPSRGH QRVARR
form :
Supplied as lyophilized form in PBS, pH7.4, containing 1mM DTT, 5% trehalose, 0.01% sarcosyl and preservative.
storage stability :
Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months. Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
tested application :
SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
other info1 :
Residues: Val1589~Arg1686. Tags Information: N-terminal His-Tag. Endotoxin Level: <1.0EU per 1ug(determined by the LAL method).
other info2 :
Predicted isoelectric point: 7.6. Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.
ncbi acc num :
NP_055087.2
ncbi gb acc num :
NM_014272.3
ncbi mol weight :
12.6kDa
ncbi summary :
The protein encoded by this gene is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family. Members of this family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene contains two C-terminal TS motifs. [provided by RefSeq, Jul 2008]
uniprot summary :
ADAMTS7: Metalloprotease that may play a role in the degradation of COMP. Protein type: Cell surface; Secreted, signal peptide; Secreted; EC 3.4.24.-; Protease; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 15q24.2. Cellular Component: proteinaceous extracellular matrix; cell surface; endoplasmic reticulum lumen. Molecular Function: protein binding; zinc ion binding; metallopeptidase activity; metalloendopeptidase activity. Biological Process: protein amino acid O-linked glycosylation; cellular protein metabolic process; proteolysis involved in cellular protein catabolic process; negative regulation of chondrocyte differentiation; post-translational protein modification