Recombinant Vascular Endothelial Growth Factor C (VEGFC) | MyBioSource MBS2010606 product information

product summary

company name :

MyBioSource

product type :

protein

product name :

Recombinant Vascular Endothelial Growth Factor C (VEGFC)

catalog :

MBS2010606

quantity :

0.01 mg

price :

185 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS2010606

products type :

Recombinant Protein

products full name :

Recombinant Vascular Endothelial Growth Factor C (VEGFC)

products short name :

Vascular Endothelial Growth Factor C (VEGFC)

other names :

vascular endothelial growth factor C; Vascular endothelial growth factor C; vascular endothelial growth factor C; VRP; flt4-L; flt4 ligand; vascular endothelial growth factor C isoform 129; vascular endothelial growth factor C isoform 184; vascular endothelial growth factor-related protein; vascular endothelial growth factor C; Flt4 ligand; Flt4-L; Vascular endothelial growth factor-related protein

products gene name :

VEGFC

other gene names :

Vegfc; Vegfc; VEGF-C; AW228853; VEGF-C; Flt4-L; VRP

uniprot entry name :

VEGFC_MOUSE

host :

E Coli

sequence length :

415

sequence :

The sequence of the target protein is listed below. AHY NTEILKSIDN EWRKTQCMPR EVCIDVGKEF GAATNTFFKP PCVSVYRCGG CCNSEGLQCM NTSTGYLSKT LFEITVPLSQ GPKPVTISFA NHTSCRCMSK LDVYRQVHSI IRR

purity :

> 95%

form :

Supplied as lyophilized form in 20mM Tris, 500mM NaCl, pH 8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative.

storage stability :

Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months. Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.

tested application :

SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)

other info1 :

Organism: Mus musculus (Mouse). Expression System: Prokaryotic expression. Residues: Ala108~Arg223 (Accession # P97953) with N-terminal His-Tag. Subcellular Location: Secreted

other info2 :

Endotoxin Level: 2 O

products description :

About the Marker: Effective Size Range: 10kDa to 70kDa. Protein bands: 10kDa, 14kDa, 18kDa, 22kDa, 26kDa, 33kDa, 44kDa and70kDa. Double intensity bands: The 26kDa, 18kDa, 10kDa bands are at doubleintensity to make location and size approximation of proteins of interestquick and easy. Ready-to-use: No need to heat, dilute or add reducing agents before use.

ncbi gi num :

6678565

ncbi acc num :

NP_033532.1

ncbi gb acc num :

NM_009506.2

uniprot acc num :

P97953

ncbi mol weight :

14.6 kDa

ncbi pathways :

Cytokine-cytokine Receptor Interaction Pathway (83248); Cytokine-cytokine Receptor Interaction Pathway (460); Focal Adhesion Pathway (198353); Focal Adhesion Pathway (83264); Focal Adhesion Pathway (478); Heart Development Pathway (672437); Hemostasis Pathway (925961); PI3K-Akt Signaling Pathway (692242); PI3K-Akt Signaling Pathway (692979); PI3K/Akt/mTOR Signaling Pathway (522982)

uniprot summary :

VEGFC: Growth factor active in angiogenesis, and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors. Homodimer; non-covalent and antiparallel. Spleen, lymph node, thymus, appendix, bone marrow, heart, placenta, ovary, skeletal muscle, prostate, testis, colon and small intestine and fetal liver, lung and kidney, but not in peripheral blood lymphocyte. Belongs to the PDGF/VEGF growth factor family. Protein type: Cell cycle regulation; Motility/polarity/chemotaxis; Secreted, signal peptide; Cytokine; Secreted. Cellular Component: extracellular space; membrane; extracellular region. Molecular Function: protein binding; growth factor activity; vascular endothelial growth factor receptor 3 binding; chemoattractant activity. Biological Process: positive regulation of neuroblast proliferation; multicellular organismal development; positive regulation of blood vessel endothelial cell migration; positive regulation of protein amino acid autophosphorylation; induction of positive chemotaxis; negative regulation of cell proliferation; organ morphogenesis; positive regulation of angiogenesis; positive regulation of peptidyl-tyrosine phosphorylation; morphogenesis of embryonic epithelium; positive regulation of protein secretion; positive chemotaxis; positive regulation of cell division; regulation of vascular endothelial growth factor receptor signaling pathway; positive regulation of cell proliferation; negative regulation of blood pressure; angiogenesis; positive regulation of cell-matrix adhesion; vascular endothelial growth factor receptor signaling pathway; cell differentiation; positive regulation of epithelial cell proliferation

size1 :

0.01 mg

price1 :

185 USD

size2 :

0.05 mg

price2 :

380

size3 :

0.1 mg

price3 :

585

more info or order :

MyBioSource product webpage